Please use this identifier to cite or link to this item:
Type
PhotoCopyright
Open access
Sustainable Development Goals
03 Saúde e Bem-EstarCollections
Metadata
Show full item record
VACINA TRÍPLICE VIRAL
Author
Affilliation
Abstract in Portuguese
A vacina sarampo, caxumba e rubéola atende aos requisitos da Agência de Vigilância Sanitária (Anvisa) para a fabricação de substâncias biológicas. Os ingredientes ativos da vacina trivalente são os vírus vivos atenuados do sarampo (cepa Schwarz), da rubéola (cepa Wistar RA27/3) e da caxumba (cepa RIT 4385 derivada da cepa Jeryl-Lynn), produzidos em substratos celulares e células diploides. Os bulks (concentrados virais) monovalentes de rubéola, sarampo e caxumba são misturados juntamente com volumes apropriados de excipientes e estabilizadores. A vacina trivalente é, então, envasada e liofilizada.
Abstract
Measles, mumps and rubella vaccine meets the requirements of the Health Surveillance Agency (Anvisa) for the manufacture of biological substances. The active ingredients of the trivalent vaccine are the measles live attenuated virus (Schwarz strain), rubella (strain Wistar RA27 / 3) and mumps (strain RIT 4385 derived from the Jeryl-Lynn strain) produced in cell substrates and diploid cells. The bulks (viral concentrates) monovalent rubella, measles and mumps, are mixed with appropriate amounts of excipients and stabilizers. The trivalent vaccine is then lyophilised and bottled.
Share