| Author | Sardi, Silvia | |
| Author | Somasekar, Sneha | |
| Author | Naccache, Samia N. | |
| Author | Bandeira, Antonio Carlos de Albuquerque | |
| Author | Tauro, Laura Beatriz | |
| Author | Campos, Gubio Soares | |
| Author | Chiu, Charles Y. | |
| Access date | 2016-07-29T18:06:30Z | |
| Available date | 2016-07-29T18:06:30Z | |
| Document date | 2016 | |
| Citation | SARDI, S. et al. Co-Infections from Zika and Chikungunya Virus in Bahia, Brazil Identified by Metagenomic Next-Generation Sequencing. Journal of Clinical Microbiology, p. 1-19, Jul. 2016. | |
| ISSN | 0095-1137 | |
| URI | https://www.arca.fiocruz.br/handle/icict/15155 | |
| Language | eng | en_US |
| Publisher | American Society for Microbiology | |
| Rights | open access | |
| Title | Co-Infections from Zika and Chikungunya Virus in Bahia, Brazil Identified by Metagenomic Next-Generation Sequencing | en_US |
| Type | Preprint | |
| DOI | 10.1128/JCM.00877-16 | |
| Abstract | Metagenomic next-generation sequencing (mNGS) of 15 patients with documented ZIKV infection in Bahia, Brazil from April 2015 to January 2016 identified co-infections with chikungunya virus (CHIKV) in 2 of 15 ZIKV PCR-positive cases (13.3%). While generally non-specific, the clinical presentation corresponding to these two CHIKV/ZIKV co-infections reflected infection by the virus present at higher titer. Aside from CHIKV and ZIKV, co-infections from other viral pathogens were not detected. The mNGS approach is promsiing for differential diagnosis of acute febrile illness and identification of co-infections, although targeted arbovirus screening may be sufficient in the current ZIKV outbreak setting. | en_US |
| Affilliation | Universidade Federal da Bahia. Instituto de Ciências da Saúde. Laboratório de Virologia. Salvador, BA, Brasil. | |
| Affilliation | University of California. Department of Laboratory Medicine. San Francisco, CA / UCSF. Abbott Viral Diagnostics and Discovery Center. San Francisco, CA, USA. | |
| Affilliation | University of California. Department of Laboratory Medicine. San Francisco, CA / UCSF. Abbott Viral Diagnostics and Discovery Center. San Francisco, CA, USA. | |
| Affilliation | Hospital Aliança. Salvador, BA, Brasil. | |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil. | |
| Affilliation | Universidade Federal da Bahia. Instituto de Ciências da Saúde. Laboratório de Virologia. Salvador, BA, Brasil. | |
| Affilliation | University of California. Department of Laboratory Medicine. San Francisco, CA, USA / UCSF. Abbott Viral Diagnostics and Discovery Center. San Francisco, CA, USA / University of California. Department of Medicine. Division of Infectious Diseases. San Francisco, CA, USA. | |
| Subject | Chikungunya virus | en_US |
| Subject | Zika Virus | en_US |
| Subject | Virus Infections | en_US |
| Subject | Arboviruses | en_US |
| Subject | PCR | en_US |
| Subject | Coinfection | en_US |
| Subject | Humans | en_US |
| Subject | Diagnosis, Differential | en_US |
| Subject | Brazil | en_US |
| Peer reviewed | Não | |
| Publication status | Não Publicado | |
