Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/15344
Title: Cultivation-independent methods reveal differences among bacterial gut microbiota in triatomine vectors of Chagas disease
Authors: Mota, Fabio Faria da
Marinho, Lourena Pinheiro
Moreira, Carlos José de Carvalho
Lima, Marli Maria
Mello, Cícero Brasileiro
Garcia, Eloi Souza
Carels, Nicolas
Azambuja, Patricia
Affilliation: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Computacional e Sistemas. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Bioquímica e Fisiologia de Insetos. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Doenças Parasitárias. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Ecoepidemiologia da Doenca de Chagas. Rio de Janeiro, RJ, Brasil.
Universidade Federal Fluminense. Laboratório de Biologia de Insetos. Niterói, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Bioquímica e Fisiologia de Insetos. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genômica Funcional e Bioinformática. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Bioquímica e Fisiologia de Insetos. Rio de Janeiro, RJ, Brasil.
Abstract: Chagas disease is a trypanosomiasis whose agent is the protozoan parasite Trypanosoma cruzi, which is transmitted to humans by hematophagous bugs known as triatomines. Even though insecticide treatments allow effective control of these bugs in most Latin American countries where Chagas disease is endemic, the disease still affects a large proportion of the population of South America. The features of the disease in humans have been extensively studied, and the genome of the parasite has been sequenced, but no effective drug is yet available to treat Chagas disease. The digestive tract of the insect vectors in which T. cruzi develops has been much less well investigated than blood from its human hosts and constitutes a dynamic environment with very different conditions. Thus, we investigated the composition of the predominant bacterial species of the microbiota in insect vectors from Rhodnius, Triatoma, Panstrongylus and Dipetalogaster genera.
Keywords: Chagas disease
Triatomine Vectors
Bacterial gut microbiota
keywords: Doença de Chagas
Triatominae
Vetores
Microbiota intestinal bacteriana
Issue Date: 2012
Publisher: Public Library of Science
Citation: MOTA, Fabio Faria da; et al. Cultivation-Independent Methods Reveal Differences among Bacterial Gut Microbiota in Triatomine Vectors of Chagas Disease. . PLoS Negl Trop Dis., v.6, n.5, e1631, 13p, May 2012.
DOI: 10.1371/journal.pntd.0001631
ISSN: 1935-2727
Copyright: open access
Appears in Collections:IOC - Artigos de Periódicos

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