| Author | Delatorre, Edson Oliveira | |
| Author | Bello, Gonzalo | |
| Author | Silva, Walter de Araujo Eyer | |
| Author | Chequer-Fernandez, Saada L. | |
| Author | Morgado, Mariza G. | |
| Author | Fernandez, José Carlos Couto | |
| Access date | 2016-09-15T12:33:52Z | |
| Available date | 2016-09-15T12:33:52Z | |
| Document date | 2012 | |
| Citation | DELATORRE, Edson Oliveira; et al. Evidence of Multiple Introductions and Autochthonous Transmission of the HIV Type 1 CRF02_AG Clade in Brazil. Aids Research and Human Retroviruses, v.28, n.10, p.1369-1372, 2012. | pt_BR |
| ISSN | 0889-2229 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/15804 | |
| Language | eng | pt_BR |
| Publisher | Mary Ann Liebert | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | HIV-1 | pt_BR |
| Subject in Portuguese | Vigilância epidemiológica | pt_BR |
| Subject in Portuguese | Rio de Janeiro | pt_BR |
| Subject in Portuguese | Linhagens virais emergentes | pt_BR |
| Title | Evidence of Multiple Introductions and Autochthonous Transmission of the HIV Type 1 CRF02_AG Clade in Brazil | pt_BR |
| Type | Article | |
| DOI | 10.1089/aid.2011.0381 | |
| Abstract | HIV-1 CRF02_AG is the most prevalent intersubtype recombinant form worldwide. Six HIV-1 samples from
patients living in Rio de Janeiro, Brazil, were subtyped as CRF02_AG at the pol gene between 2004 and 2011. To
trace the origin of these viruses, they were compared with 793 CRF02_AG pol sequences of African origin and
another four Brazilian CRF02_AG pol sequences previously described. Phylogenetic analysis reveals that there
have been at least four introductions of the CRF02_AG clade in Brazil, as signified by the presence of four
phylogenetically distinct lineages, probably originated from western African countries (Benin, Ghana, and
Guinea-Bissau). At least two CRF02_AG Brazilian lineages were successful in getting established and disseminated
throughout the Rio de Janeiro state, with evidence of both horizontal and vertical transmission. Continuous
epidemiological surveillance of HIV-1 strains circulating in Brazil is of paramount importance to the
early detection of newly emerging viral lineages. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Hospital Universitário Gafreé Guinle. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | HIV-1 strains | pt_BR |
| Subject | Rio de Janeiro | pt_BR |
| Subject | epidemiological surveillance | pt_BR |
| Subject | HIV-1 CRF02_AG | pt_BR |
| Subject | newly emerging viral lineages | pt_BR |
| e-ISSN | 1931-8405 | |
| Embargo date | 2030-01-01 | |
