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LINEAGE-SPECIFIC SEROLOGY CONFIRMS BRAZILIAN ATLANTIC FOREST LION TAMARINS, LEONTOPITHECUS CHRYSOMELAS AND LEONTOPITHECUS ROSALIA, AS RESERVOIR HOSTS OF TRYPANOSOMA CRUZI II (TCII)
Kerr, Charlotte L. et al. | Date Issued: 2016
Author
Kerr, Charlotte L.
Bhattacharyya, Tapan
Xavier, Samanta C.C.
Barros, Juliana H.
Lima, Valdirene S.
Jansen, Ana M.
Miles, Michael A.
Affilliation
London School of Hygiene and Tropical Medicine. Faculty of Infectious and Tropical Diseases. London, UK.
London School of Hygiene and Tropical Medicine. Faculty of Infectious and Tropical Diseases. London, UK.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanossomatídeos. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanossomatídeos. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanossomatídeos. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanossomatídeos. Rio de Janeiro, RJ. Brasil.
ondon School of Hygiene and Tropical Medicine. Faculty of Infectious and Tropical Diseases. London, UK.
Abstract
Trypanosoma cruzi, the agent of Chagas disease in humans, has a vast reservoir of mammalian hosts in the Americas, and is classified into six genetic lineages, TcI-TcVI, with a possible seventh, TcBat. Elucidating enzootic cycles of the different lineages is important for understanding the ecology of this parasite, the emergence of new outbreaks of Chagas disease and for guiding control strategies. Direct lineage identification by genotyping is hampered by limitations of parasite isolation and culture. An indirect method is to identify lineage-specific serological reactions in infected individuals; here we describe its application with sylvatic Brazilian primates.
Keywords in Portuguese
Trypanosoma cruzi
ELISA
Sorologia
Primatas
Doença de Chagas
Linhagem específica
 
Keywords
Trypanosoma cruzi
ELISA
Serology
Lineage-specific
Chagas disease
Primates
 
Publisher
BioMed Central
Citation
KERR, Charlotte L. et al. Lineage-specific serology confirms Brazilian Atlantic forest lion tamarins, Leontopithecus chrysomelas and Leontopithecus rosalia, as reservoir hosts of Trypanosoma cruzi II (TcII). Parasites & Vectors, v.9:584, 10p, 2016.
DOI
10.1186/s13071-016-1873-y
ISSN
1756-3305