Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/18200
Title: 7,7-Dimethylaporphine and Other Alkaloids from the Bark of Guatteria friesiana
Authors: Costa, Emmanoel Vilaça
Pinheiro, Maria Lúcia Belém
Maia, Beatriz Helena Lameiro de Noronha Sales
Marques, Francisco de Assis
Ruiz, Ana Lúcia Tasca Gois
Marchetti, Gabriela Menezes
Carvalho, João Ernesto de
Soares, Milena Botelho Pereira
Costa, Cinara Oliveira D' Sousa
Galvão, Alexandre Francisco Cerqueira
Lopes, Norberto Peporine
Koolen, Hector Henrique Ferreira
Bezerra, Daniel Pereira
Barison, Andersson
Affilliation: Federal University of Amazonas. Department of Chemistry. Manaus, AM, Brazil
Federal University of Amazonas. Department of Chemistry. Manaus, AM, Brazil
Federal University of Paraná. Department of Chemistry. Curitiba, PR, Brazil
Federal University of Paraná. Department of Chemistry. Curitiba, PR, Brazil
University of Campinas. Chemical, Biological and Agricultural Pluridisciplinary Research Center/CPQBA. Paulínia, SP, Brazil
University of Campinas. Chemical, Biological and Agricultural Pluridisciplinary Research Center/CPQBA. Paulínia, SP, Brazil
University of Campinas. Chemical, Biological and Agricultural Pluridisciplinary Research Center/CPQBA. Paulínia, SP, Brazil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / São Rafael Hospital. Biotechnology and Cell Therapy Center. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
University of São Paulo. Faculty of Pharmaceutical Sciences of Ribeirão Preto. Department of Chemistry and Physics. Ribeirão Preto, SP, Brasil
Amazonas State University. DeMpSter Mass Spectrometry Group. Manaus, AM, Brazil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Federal University of Paraná. Department of Chemistry. Curitiba, PR, Brazil
Abstract: Phytochemical investigation of the bark of Guatteria friesiana afforded 12 new aporphines (1-12), along with nine known alkaloids (13-21). The structures of the new alkaloids were determined on the basis of spectroscopic data interpretation. The cytotoxic activity of the isolated compounds against a small panel of tumor cell lines was assessed using the Alamar blue assay.
Keywords: Guatteria Friesiana
Plant bark
Plants Alkaloids
Essential oil
Brazil
keywords: Guatteria Friesiana
Casca de planta
Alcaloides de plantas
Óleos essenciais
Brasil
Issue Date: 2016
Publisher: American Chemical Society
Citation: COSTA, E. V. et al. 7,7-Dimethylaporphine and Other Alkaloids from the Bark of Guatteria friesiana. Journal of Natural Products, v. 79, p. 1524−1531, 2016.
DOI: 10.1021/acs.jnatprod.5b01037
ISSN: 0163-3864
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

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