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2018-03-11
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THE CHALLENGE OF ASSESSING MICROCEPHALY IN THE CONTEXT OF THE ZIKA VIRUS EPIDEMIC
Quintó, Llorenç et al. | Date Issued: 2017
Author
Quintó, Llorenç
García-Basteiro, Alberto L.
Bardají, Azucena
González, Raquel
Padilla, Norma
Martinez-Espinosa, Flor E.
Arévalo-Herrera, Myriam
Macete, Eusébio
Menéndez, Clara
Affilliation
Hospital Clínic-Universitat de Barcelona. Barcelona Centre for International Health Research (CRESIB). ISGlobal. Barcelona, Spain / CIBER Epidemiología y Salud Pública (CIBERESP). Barcelona, Spain.
Hospital Clínic-Universitat de Barcelona. Barcelona Centre for International Health Research (CRESIB). ISGlobal. Barcelona, Spain / Centro de Investigação em Saúde de Manhiça (CISM). Maputo, Mozambique / Amsterdam Institute for Global Health and Development (AIGHD). Amsterdam, Netherlands.
Hospital Clínic-Universitat de Barcelona. Barcelona Centre for International Health Research (CRESIB). ISGlobal. Barcelona, Spain / CIBER Epidemiología y Salud Pública (CIBERESP). Barcelona, Spain / Centro de Investigação em Saúde de Manhiça (CISM). Maputo, Mozambique.
Hospital Clínic-Universitat de Barcelona. Barcelona Centre for International Health Research (CRESIB). ISGlobal. Barcelona, Spain / CIBER Epidemiología y Salud Pública (CIBERESP). Barcelona, Spain / Centro de Investigação em Saúde de Manhiça (CISM). Maputo, Mozambique.
Universidad del Valle da Guatemala (CES-UVG). Centro de Estudios en Salud. Guatemala, Guatemala.
Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Amazônia, AM, Brasil / Fundação de Medicina Tropical Dr. Heitor Vieira Dourado (FMT-HVD). Gerência de Malária. Manaus, AM, Brasil.
Universidad del Valle. Facultad de Salud. Centro Internacional de Vacunas (CIV). Cali, Colombia.
Centro de Investigação em Saúde de Manhiça (CISM). Maputo, Mozambique / Ministry of Health. National Directare of Health. Maputo, Mozambique.
Hospital Clínic-Universitat de Barcelona. Barcelona Centre for International Health Research (CRESIB). ISGlobal. Barcelona, Spain / CIBER Epidemiología y Salud Pública (CIBERESP). Barcelona, Spain / Centro de Investigação em Saúde de Manhiça (CISM). Maputo, Mozambique.
Abstract
The present article examines the impact of the current limitations of the microcephaly definition in the context of the Zika virus outbreak. It highlights its dependence on the method used for determining gestational age and other anthropometric parameters, and includes original results of prevalence of microcephaly in four countries from two different continents (Mozambique, Brazil, Guatemala and Colombia). Alternative definitions of microcephaly are proposed to allow the identification of true cases of microcephaly in a more accurate manner.
Keywords in Portuguese
Microcefalia
Zika virus
Moçambique
Brasil
Guatemala
Colômbia
 
Keywords
Microcephaly
Zika virus
Mozambique
Brazil
Guatemala
Colombia
 
DeCS
Microcefalia
Zika virus
Moçambique
Brasil
Guatemala
Colômbia
 
Publisher
Oxford University Press
Citation
QUINTÓ Llorenç et al. The challenge of assessing microcephaly in the context of the zika virus epidemic. Journal of Tropical Pediatrics, p. 1–4, 2017.
DOI
10.1093/tropej/fmx015
ISSN
0142-6338
Notes
The authors are grateful to all the pregnant women, the medical staff and technicians who have participated in the studies.