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https://www.arca.fiocruz.br/handle/icict/18665
EXON-INTRON STRUCTURE AND SEQUENCE VARIATION OF THE CALRETICULIN GENE AMONG RHIPICEPHALUS SANGUINEUS GROUP TICKS
Grupo Rhipicephalus sanguineus
Evolução de Intron
Polimorfismo de presença-ausência intrônica
Controle de carrapatos
Marcadores genéticos
Rhipicephalus sanguineus group
Intron evolution
Intron presence-absence polymorphism
Tick control
Genetic markers
Variação Genética
Rhipicephalus / genética
Análise de Sequência , DNA
Exons
Introns
Author
Affilliation
Sapienza University of Rome. Department of Environmental Biology. Rome, Italy.
University of Bari. Department of Veterinary Medicine. Valenzano, Bari, Italy.
University of Bari. Department of Veterinary Medicine. Valenzano, Bari, Italy / Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Imunologia. Recife, PE, Brasil.
Sapienza University of Rome. Department of Environmental Biology. Rome, Italy.
University of Bari. Department of Veterinary Medicine. Valenzano, Bari, Italy.
University of Bari. Department of Veterinary Medicine. Valenzano, Bari, Italy.
Sapienza University of Rome. Department of Environmental Biology. Rome, Italy.
University of Bari. Department of Veterinary Medicine. Valenzano, Bari, Italy.
University of Bari. Department of Veterinary Medicine. Valenzano, Bari, Italy / Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Imunologia. Recife, PE, Brasil.
Sapienza University of Rome. Department of Environmental Biology. Rome, Italy.
University of Bari. Department of Veterinary Medicine. Valenzano, Bari, Italy.
University of Bari. Department of Veterinary Medicine. Valenzano, Bari, Italy.
Sapienza University of Rome. Department of Environmental Biology. Rome, Italy.
Abstract
Calreticulin proteins (CRTs) are important components of tick saliva, which is involved in the blood meal success, pathogen transmission and host allergic responses. The characterization of the genes encoding for salivary proteins, such as CRTs, is pivotal to understand the mechanisms of tick-host interaction during blood meal and to develop tick control strategies based on their inhibition. In hard ticks, crt genes were shown to have only one intron with conserved position among species. In this study we investigated the exon-intron structure and variation of the crt gene in Rhipicephalus spp. ticks in order to assess the crt exon-intron structure and the potential utility of crt gene as a molecular marker.
Keywords in Portuguese
Carrapato duroGrupo Rhipicephalus sanguineus
Evolução de Intron
Polimorfismo de presença-ausência intrônica
Controle de carrapatos
Marcadores genéticos
Keywords
Hard tickRhipicephalus sanguineus group
Intron evolution
Intron presence-absence polymorphism
Tick control
Genetic markers
DeCS
Calreticulina / genéticaVariação Genética
Rhipicephalus / genética
Análise de Sequência , DNA
Exons
Introns
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