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CAPSULAR SWITCHING IN INVASIVE NEISSERIA MENINGITIDIS, BRAZIL
Castiñeiras, Terezinha M. P. P. et al. | Date Issued: 2012
Author
Castiñeiras, Terezinha M. P. P.
Barroso, David E.
Marsh, Jane W.
Tulenko, Mary M.
Krauland, Mary G.
Rebelo, Maria C.
Harrison, Lee H.
Affilliation
Universidade Federal do Rio de Janeiro. Escola de Medicina. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ. Brasil.
University of Pittsburgh. Pittsburgh, Pennsylvania, USA.
University of Pittsburgh. Pittsburgh, Pennsylvania, USA.
University of Pittsburgh. Pittsburgh, Pennsylvania, USA.
Secretaria de Estado de Saúde do Rio de Janeiro. Laboratório Central Noel Nutels. Rio de Janeiro, RJ, Brasil.
University of Pittsburgh. Pittsburgh, Pennsylvania, USA.
Abstract
During the 1990s, an epidemic of B:4 Neisseria meningitidis infections affected Brazil. Subsequent increase in C:4 disease suggested B → C capsular switching. This study identified B → C switches within the sequence type 32 complex. Substantial disease related to capsular switching emphasizes the need for surveillance of circulating meningococcal strains to optimize disease control.
Keywords in Portuguese
Neisseria meningitidis
Brasil
 
Keywords
Neisseria meningitidis
Brazil
 
Publisher
Centers for Disease Control and Prevention
Citation
CASTIÑEIRAS, Terezinha M. P. P. et al. Capsular Switching in Invasive Neisseria meningitidis, Brazil. Emerging Infectious Diseases, v.18, n.8, 3p, Aug. 2012.
DOI
10.3201/eid1808.111344
ISSN
1080-6040