Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/1872
Title: Limited evidence of HCV transmission in stable heterosexual couples from Bahia, Brazil
Authors: Bessa, Márcia
Rodart, Itatiana Ferreira
Menezes, Gisele Barreto Lopes
Carmo, Theomira Mauadie de Azevedo
Athanazio, Daniel Abensur
Reis, Mitermayer Galvão dos
Affilliation: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Abstract: HCV infected patients frequently ask their physician about the risk of transmission to their partners. Although it is easy to answer that the risk does exist, it is difficult to quantify. We studied the transmission of HCV infection in stable heterosexual couples: anti-HCV positive patients in hemodialytic therapy and their partners. Thirty-four couples were tested by third generation ELISA and RIBA. Blood samples of anti-HCV positive patients were evaluated by RT-PCR and detected sequences were genotyped by restriction fragment length polymorphism. Concordance of infection was observed in only one couple in which both subjects were in dialytic therapy. One other partner had two positive ELISA tests and an indeterminate RIBA, with negative RT-PCR, which may suggest a false positive or a previous resolved infection. Either sexual relations, sharing of personal items and history of parenteral exposure (hemodialysis, blood transfusion) could explain transmission in the only couple with concordant infection. We observed, in accordance with previous reports, that this risk is minimal or negligible in stable heterosexual couples.
Keywords: Hepatitis C
Renal dialysis
Sexual partners
Sexually transmitted diseases
DeCS: Hepatite C
Anticorpos Anti-Hepatite C
Heterossexualidade/SN
Diálise Renal /AE
Cônjuges/SN
Parceiros Sexuais
Reação em Cadeia da Polimerase Via Transcriptase Reversa
Issue Date: 2009
Citation: BESSA, M. et al. Limited evidence of HCV transmission in stable heterosexual couples from Bahia, Brazil. Brazilian Journal of Infectious Diseases, v.13, n.4, p.262-265, 2009.
DOI: 10.1590/S1413-86702009000400004
ISSN: 1413-8670
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

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