Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/19321
Title: Genetic structure of Lutzomya (Nyssomyia) Intemedia populations from two ecologic regions in Brazil where transmission of Leishmania (Vianna) Braziliensis reflects distinct eco-epidemiologic features
Authors: Rocha, Leonardo de Souza
Falqueto, Aloísio
Santos, Claudiney Biral dos
Grimaldi Jr., Gabriel
Cupolillo, Elisa
Affilliation: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Pesquisas em Leishmanioses. Rio de Janeiro, RJ. Brasil.
Universidade Federal do Espírito Santo. Unidade de Medicina Tropical. Vitória, ES, Brasil.
Universidade Federal do Espírito Santo. Unidade de Medicina Tropical. Vitória, ES, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Pesquisas em Leishmanioses. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Pesquisas em Leishmanioses. Rio de Janeiro, RJ. Brasil.
Abstract: Randomly amplified polymorphic DNA (RAPD) analysis was performed to infer the magnitude and pattern of genetic differentiation among Lutzomyia (Nyssomyia) intermedia populations from two ecologic regions in southeast Brazil where transmission of American cutaneous leishmaniasis (ACL) by L. (Viannia) braziliensis reflects distinct eco-epidemiologic features. Two hundred thirty-five bands from six primers were analyzed for genetic variation within and between sand fly populations. A lower level of intrapopulational variability was found in domestic sand flies (compared with the peridomestic population). Gene flow FST estimates indicated homogeneity in the studied population, with limited population substructuring, but with a tendency of sand fly vectors to form clusters by micro-habitat (domestic and peridomestic). The level of genetic structuring of Lu. intermedia population from each ecologic region is distinct and may reflect association or independence between the domestic and the peridomestic habitats in rural and periurban areas, respectively, both reflecting distinct characteristics of the transmission cycle of ACL.
Keywords: Leishmania (Viannia) braziliensis
Brazil
Transmission
American cutaneous leishmaniasis
Lutzomyia (Nyssomyia) intermedia
keywords: Leishmania braziliensis
Brasil
Transmissão
Lutzomyia (Nyssomyia) intermedia
Issue Date: 2007
Publisher: American Society of Tropical Medicine and Hygiene
Citation: ROCHA, Leonardo de Souza; et al. Genetic structure of Lutzomyia (Nyssomyia) Intermedia populations from two ecologic regions in Brazil. where transmission of Leishmania (Viannia) Braziliensis reflects distinct eco-epiudemiologic features. Am. J. Trop. Med. Hyg., v.76, n.3, p.559–565, 2007.
ISSN: 0002-9637
Copyright: restricted access
Appears in Collections:IOC - Artigos de Periódicos

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