Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/19399
Title: Two decades of tuberculosis in a city in Northeastern Brazil: advances and challenges in time and space
Authors: Silva, Amanda Priscila de Santana Cabral
Souza, Wayner Vieira de
Albuquerque, Maria de Fátima Pessoa Militão de
Affilliation: Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Núcleo de Estudos em Saúde Coletiva. Recife, PE, Brasil.
Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Núcleo de Estudos em Saúde Coletiva. Recife, PE, Brasil.
Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Núcleo de Estudos em Saúde Coletiva. Recife, PE, Brasil.
Abstract: Introduction: This study presents two decades of epidemiological data on tuberculosis (TB), in order to understanding the disease profile and its spatiotemporal dynamics. Methods: This descriptive study was performed in the City of Olinda/Pernambuco, Brazil, from 1991-2010, and it analyzed new patients with TB living in the city. We used the χ²-test with a p-value <0.05 to identify differences in trends. Incidence and cluster distribution were identified using spatial scan statistics. Results: In total, 6202 new cases were recorded during the two decades. The highest incidence occurred in 1995 (110 cases/100,000 inhabitants), and the lowest occurred in 2009 (65 cases/100,000 inhabitants) (β=-1.44; R²=0.43; p=0.0018). The highest mortality occurred in 1998 (16 deaths/100,000 inhabitants), and the lowest occurred in 2008 (5 deaths/100,000 inhabitants) (β=-0.19; R²=0.17; p=0.07). There was a male predominance (65%), and ages ranged from 20-49 years (65%). There was a substantial increase in the number of patients that were cured after treatment (60% to 67%; p<0.001) as well as those tested for HIV (1.9% to 58.5%; p<0.001). During the first decade, clusters with p-values <0.05 included 29% of the total notified cases, and in the second decade, that percentage was 12%. CONCLUSIONS We observed a decreasing trend in incidence, which was significant, and mortality rates, which was not significant. The increased number of laboratory tests performed reflects advances in surveillance, and a reduction in the proportion of cases in primary clusters suggests, among other things, that the disease is spreading across the region.
Keywords: Tuberculosis
Epidemiological surveillance
Spatial analysis
DeCS: Tuberculose Pulmonar / epidemiologia
Brasil / epidemiologia
Issue Date: 2016
Citation: SILVA, A. P. DE S. C.; SOUZA, W. V. DE; ALBUQUERQUE, M. DE F. P. M. DE. Two decades of tuberculosis in a city in Northeastern Brazil: advances and challenges in time and space. Revista da Sociedade Brasileira de Medicina Tropical, v. 49, n. 2, p. 211–221, abr. 2016.
DOI: 10.1590/0037-8682-0065-2016
ISSN: 1678-9849
Copyright: open access
Appears in Collections:PE - IAM - Artigos de Periódicos

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