Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/19484
Title: Accuracy of chimeric proteins in the serological diagnosis of chronic chagas disease - a Phase II study
Authors: Santos, Fred Luciano Neves
Celedon, Paola Alejandra Fiorani
Zanchin, Nilson Ivo Tonin
Souza, Wayner Vieira de
Silva, Edimilson Domingos da
Foti, Leonardo
Krieger, Marco Aurélio
Gomes, Yara de Miranda
Affilliation: Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil / Oswaldo Cruz Foundation. Oswaldo Cruz Institute. Chagas Disease Integrated Program. Rio de Janeiro, RJ, Brazil.
Molecular Biology Institute of Paraná. Curitiba, PR, Brazil.
Oswaldo Cruz Foundation. Carlos Chagas Institute. Curitiba, Paraná, Brazil.
Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.
Oswaldo Cruz Foundation. Oswaldo Cruz Institute. Chagas Disease Integrated Program. Rio de Janeiro, RJ, Brazil / Oswaldo Cruz Foundation. Bio-Manguinhos. Rio de Janeiro, RJ, Brazil.
Molecular Biology Institute of Paraná. Curitiba, PR, Brazil / Oswaldo Cruz Foundation. Carlos Chagas Institute. Curitiba, Paraná, Brazil.
Oswaldo Cruz Foundation. Oswaldo Cruz Institute. Chagas Disease Integrated Program. Rio de Janeiro, RJ, Brazil / Molecular Biology Institute of Paraná. Curitiba, PR, Brazil / Oswaldo Cruz Foundation. Carlos Chagas Institute. Curitiba, Paraná, Brazil.
Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil / Oswaldo Cruz Foundation. Oswaldo Cruz Institute. Chagas Disease Integrated Program. Rio de Janeiro, RJ, Brazil.
Abstract: The performance of current serologic tests for diagnosing chronic Chagas disease (CD) is highly variable. The search for new diagnostic markers has been a constant challenge for improving accuracy and reducing the number of inconclusive results.
keywords: Doença de Chagas
Diagnóstico
Testes Sorológicos
DeCS: Anticorpos, protozoários / sangue
Antígenos, protozoários / imunologia
Doença de Chagas / diagnóstico
Proteínas Recombinantes / imunologia
Trypanosoma cruzi / imunologia
Issue Date: 2017
Citation: SANTOS, F. L. N. et al. Accuracy of chimeric proteins in the serological diagnosis of chronic chagas disease – a Phase II study. PLOS Neglected Tropical Diseases, v. 11, n. 3, p. 1-20, 8 mar. 2017.
DOI: 10.1371/journal.pntd.0005433
ISSN: 1935-2735
Copyright: open access
Appears in Collections:Biomanguinhos - Artigos de Periódicos
IOC - Artigos de Periódicos
PR - ICC - Artigos de Periódicos
PE - IAM - Artigos de Periódicos

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