Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/20625
Title: Leprosy reaction as a manifestation of immune reconstitution inflammatory syndrome: a case series of a Brazilian cohort
Authors: Menezes, Vinicius Martins
Sales, Anna Maria
Illarramendi, Ximena
Miranda, Alice
Morgado, Mariza Gonçalves
Gutierrez-Galhardo, Maria Clara
Sarno, Euzenir Nunes
Nery, José Augusto da Costa
Affilliation: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ. Brasil.
Abstract: Several case reports have demonstrated that the immune reconstitution inflammatory syndrome induces reversal reaction in HIV and leprosy-coinfected patients. The present study describes 10 cases of immune reconstitution inflammatory-associated reversal reaction. The patients evolved satisfactorily despite presenting a more severe form of the disease and the fact that three required an additional use of corticoids. The present study, the largest case series published to date, demonstrates that leprosy reaction is a manifestation of immune reconstitution.
Keywords: Leprosy
inflammatory syndrome
Brazil
immune reconstitution
keywords: Hanseníase
Síndrome inflamatória
Brasil Central
Issue Date: 2009
Publisher: Lippincott, Williams & Wilkins
Citation: MENEZES, Vinícius Martins; et al. Leprosy reaction as a manifestation of immune reconstitution inflammatory syndrome: a case series of a Brazilian cohort. AIDS, v.23, p. 637-643, 2009.
DOI: 10.1097/QAD.0b013e3283291405
ISSN: 0269-9370
Copyright: restricted access
Appears in Collections:IOC - Artigos de Periódicos

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