| Author | Silva, Ana Maria Moura da | |
| Author | Lima, Maria Regina D'Império | |
| Author | Nishikawa, Z. A. K | |
| Author | Brodskyn, Claudia Ida | |
| Author | Santos, Maria Cristina dos | |
| Author | Furtado, Maria de Fátima Domingues | |
| Author | Silva, Wilmar Dias da | |
| Author | Albuquerque, Ivan da Mota e | |
| Access date | 2017-08-17T18:00:09Z | |
| Available date | 2017-08-17T18:00:09Z | |
| Document date | 1990 | |
| Citation | SILVA, A. M. M. et al. Antigenic cross-reactivity of venoms obtained from snakes of genus bothrops. Toxicon, v. 28, n. 2, p. 181-188, 1990. | pt_BR |
| ISSN | 0041-0101 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/20672 | |
| Description | Brodskyn, Claudia Ida “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”. | pt_BR |
| Language | eng | pt_BR |
| Publisher | Elsevier | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Bothrops | pt_BR |
| Subject in Portuguese | Venenos de serpentes | pt_BR |
| Subject in Portuguese | Envenenamento por cobra | pt_BR |
| Subject in Portuguese | Animais | pt_BR |
| Subject in Portuguese | Elisa | pt_BR |
| Title | Antigenic cross-reactivity of venoms obtained from snakes of genus bothrops | pt_BR |
| Type | Article | pt_BR |
| Abstract | Antigenic cross-reactivity was studied
among the components of venoms from nine species of the genus Bothrops
using species-specific antivenoms . Sera titration by DOT-ELISA detected
similar levels of antibody when either homologous or heterologous antigens
were used. Transblotted antigens, after SDS-PAGE fractionation, were also
revealed by homologous and heterologous antivenoms . Antigens with mol. wt
greater than 30,000 seemed to be the most cross-reactive . Antigens of about
24,000 mol. wt were poorly immunogenic. Antigens between 14-18,000 mol. wt
cross-reacted only with B. moojeni, B.jararacussu, B. neuwiedi and B. pradoi
venoms. Neutralization of the lethality of B. jararaca venom was observed by
homologous and heterologous antivenoms . | pt_BR |
| Affilliation | Instituto Butantan. Centro de Imunologia. São Paulo, SP, Brasil | pt_BR |
| Affilliation | Universidade de São Paulo. Instituto de Ciências Biomédicas. Departamento de Imunologia. Säo Paulo, SP, Brasil | pt_BR |
| Affilliation | Instituto Butantan. Secçäo de Concentração de Soros. São Paulo, SP, Brasil | pt_BR |
| Affilliation | Instituto Butantan. Centro de Imunologia. São Paulo, SP, Brasil | pt_BR |
| Affilliation | Universidade de São Paulo. Instituto de Ciências Biomédicas. Departamento de Imunologia. Säo Paulo, SP, Brasil | pt_BR |
| Affilliation | Instituto Butantan. Seção de Venenos. São Paulo, SP, Brasil | pt_BR |
| Affilliation | Instituto Butantan. Laboratório Especial de Imunoquimica. São Paulo, SP, Brasil | pt_BR |
| Affilliation | Instituto Butantan. Centro de Imunologia. São Paulo, SP, Brasil | pt_BR |
| Subject | Bothrops | pt_BR |
| Subject | Snake venom | pt_BR |
| Subject | Snake venom | pt_BR |
| Subject | Animals | pt_BR |
| Subject | Elisa | pt_BR |
