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Title: Population-Based Multicentric Survey of Hepatitis B Infection and Risk Factors in the North, South, and Southeast Regions of Brazil, 10-20 Years After the Beginning of Vaccination
Authors: Ximenes, Ricardo A. A.
Figueiredo, Gerusa M.
Cardoso, Maria Regina A.
Stein, Airton T.
Moreira, Regina C.
Coral, Gabriela
Crespo, Deborah
Dos Santos, Alex A.
Montarroyos, Ulisses R.
Braga, Maria Cynthia
Pereira, Leila M M B
Affilliation: Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil
Abstract: A population-based hepatitis survey was carried out to estimate the prevalence of hepatitis B virus (HBV) infection and its predictive factors for the state capitals from the north, south, and southeast regions of Brazil. A multistage cluster sampling was used to select, successively, census tracts, blocks, households, and residents in the age group 10-69 years in each state capital. The prevalence of hepatitis B surface antigen (HBsAg) was lower than 1% in the north, southeast, and south regions. Socioeconomic condition was associated with HBV infection in north and south regions. Variables related to the blood route transmission were associated with HBV infection only in the south whereas those related to sexual behavior were associated with HBV infection in the north and south regions. Drug use was associated in all regions, but the type of drug differed. The findings presented herein highlight the diversity of the potential transmission routes for hepatitis B transmission in Brazil. In one hand, it reinforces the importance of national control strategies of large impact already in course (immunization of infants, adolescents, and adults up to 49 years of age and blood supply screening). On the other hand, it shows that there is still room for further control measures targeted to different groups within each region.
Keywords: Adolescent
Age Factors
Health Surveys
Hepatitis B
Middle Aged
Risk Factors
Sexually Transmitted Diseases, Viral
Socioeconomic Factors
Substance Abuse, Intravenous
Young Adult
keywords: Vacinas contra Hepatite B
Hepatite B
DeCS: Adolescente
Hepatite B
Vacinas contra Hepatite B
Fatores Etários
Inquéritos Epidemiológicos
Fatores de risco
Doenças Virais Sexualmente Transmissíveis
Fatores Socioeconômicos
Abuso de Substâncias por Via Intravenosa
Adulto Jovem
Issue Date: 2015
Citation: XIMENES, R. A. A. et al. Population-Based Multicentric Survey of Hepatitis B Infection and Risk Factors in the North, South, and Southeast Regions of Brazil, 10-20 Years After the Beginning of Vaccination. The American Journal of Tropical Medicine and Hygiene, v. 93, n. 6, p. 1341–1348, dez. 2015.
DOI: 10.4269/ajtmh.15-0216
ISSN: 1476-1645
Copyright: open access
Appears in Collections:PE - IAM - Artigos de Periódicos

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