| Author | Vermelho, Alane Beatriz | |
| Author | Branquinha, Marta Helena | |
| Author | d`Avila-Levy, Claudia M. | |
| Author | Santos, André Luis Souza dos | |
| Author | Dias, Edilma Paraguai de Souza | |
| Author | Melo, Ana Cristina Nogueira de | |
| Access date | 2017-09-16T14:55:19Z | |
| Available date | 2017-09-16T14:55:19Z | |
| Document date | 2010 | |
| Citation | VERMELHO, Alane Beatriz; et al. Biological roles of Peptidases in Trypanosomatids. The Open Parsitology Journal, v.4, p.5-23, 2010. | pt_BR |
| ISSN | 1874-4214 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/21040 | |
| Language | eng | pt_BR |
| Publisher | Bentham Open | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Peptidases | pt_BR |
| Subject in Portuguese | Tripanosomatídeos | pt_BR |
| Subject in Portuguese | Metaloproteases | pt_BR |
| Subject in Portuguese | peptidases de serina | pt_BR |
| Subject in Portuguese | Peptidases de cisteína | pt_BR |
| Title | Biological Roles of Peptidases in Trypanosomatids | pt_BR |
| Type | Article | |
| Abstract | In this review, we report the recent developments in the characterization of peptidases and their possible biological functions in the Trypanosomatidae family. The focus will be on peptidases from Trypanosoma cruzi, Leishmania spp., African trypanosomes and plant and insect trypanosomatids. There are numerous events in parasite development where the involvement of peptidases has been established, and they will be approached in the present review. Also in this review we will discuss the central roles have been proposed for peptidases in diverse processes such as virulence, host cell interaction and invasion, catabolism of host proteins, differentiation, cell cycle progression and both stimulation and evasion of host immune responses. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Instituto de Microbiologia Prof. Paulo de Góes. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Instituto de Microbiologia Prof. Paulo de Góes. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Bioquímica e Biologia Celular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Instituto de Microbiologia Prof. Paulo de Góes. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Instituto de Microbiologia Prof. Paulo de Góes. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Instituto de Microbiologia Prof. Paulo de Góes. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Subject | Peptidases | pt_BR |
| Subject | Trypanosomatids | pt_BR |
| Subject | Cruzipain | pt_BR |
| Subject | Cysteine peptidases | pt_BR |
| Subject | Serina peptidases | pt_BR |
| Subject | Metallopeptidases | pt_BR |
