| Author | Barbosa Júnior, Walter Lins | |
| Author | Araújo, Paulo Sérgio Ramos de | |
| Author | Andrade, Luiz Dias de | |
| Author | Santos, Ana Maria Aguiar dos | |
| Author | Silva, Maria Almerice Lopes da | |
| Author | Dantas-Torres, Filipe | |
| Author | Medeiros, Zulma | |
| Access date | 2017-09-19T13:16:54Z | |
| Available date | 2017-09-19T13:16:54Z | |
| Document date | 2015 | |
| Citation | BARBOSA JÚNIOR, Walter Lins et al. Rapid Tests and the Diagnosis of Visceral Leishmaniasis and Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Coinfection. The American Journal of Tropical Medicine and Hygiene, v. 93, n. 5, p. 967–969, nov. 2015. | pt_BR |
| ISSN | 1476-1645 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/21055 | |
| Language | por | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Infecções por HIV | pt_BR |
| Subject in Portuguese | Leishmaniose Visceral | pt_BR |
| Title | Rapid Tests and the Diagnosis of Visceral Leishmaniasis and Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Coinfection | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.4269/ajtmh.14-0798 | |
| Abstract | After the emergence of the human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS), the number of visceral leishmaniasis (VL)-HIV/AIDS coinfections has increased worldwide. Herein, we assessed the usefulness of an rK39-based immunochromatographic test (rK39 ICT) (DiaMed-IT LEISH(®); DiaMed AG, Cressier-sur-Morat, Switzerland) and a latex agglutination test (KAtex; Kalon Biological, Guildford, United Kingdom) for urinary antigen detection to diagnose VL in 15 HIV/AIDS patients from northeastern Brazil. VL diagnosis was based on clinical findings, cytology, serology, parasite DNA, and/or urinary antigen detection. VL was confirmed in seven out of 15 HIV/AIDS patients. Only three patients were positive in bone marrow cytology, three patients were conventional polymerase chain reaction (PCR) positive, while six were real-time PCR positive. All patients were direct agglutination test (DAT) (Royal Tropical Institute, Amsterdam, The Netherlands) positive; of these, four were positive by rK39 ICT and five by KAtex. Large-scale studies are needed to validate the use of the KAtex in the national public health laboratory network in Brazil, aiming at improving the diagnosis of VL in HIV/AIDS patients in this country. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil | pt_BR |
| Subject | Adult | pt_BR |
| Subject | Agglutination Tests | pt_BR |
| Subject | Antigens, Protozoan | pt_BR |
| Subject | Biomarkers | pt_BR |
| Subject | Coinfection | pt_BR |
| Subject | Female | pt_BR |
| Subject | HIV Infections | pt_BR |
| Subject | Humans | pt_BR |
| Subject | Immunochromatography | pt_BR |
| Subject | Latex Fixation Tests | pt_BR |
| Subject | Leishmaniasis, Visceral | pt_BR |
| Subject | Male | pt_BR |
| Subject | Middle Aged | pt_BR |
| Subject | Protozoan Proteins | pt_BR |
| Subject | Reproducibility of Results | pt_BR |
| Subject | Sensitivity and Specificity | pt_BR |
| Subject | Young Adult | pt_BR |
| Subject | complications | pt_BR |
| Subject | diagnosis | pt_BR |
| Subject | methods | pt_BR |
| DeCS | Infecções por HIV | pt_BR |
| DeCS | Leishmaniose Visceral | pt_BR |
| DeCS | Adulto | pt_BR |
| DeCS | Humanos | pt_BR |
| DeCS | Feminino | pt_BR |
| DeCS | Masculino | pt_BR |
| DeCS | Testes de Aglutinação | pt_BR |
| DeCS | Biomarcadores | pt_BR |
| DeCS | Coinfecção | pt_BR |
| DeCS | Infecções por HIV | pt_BR |
| DeCS | Imunocromatografia | pt_BR |
| DeCS | Testes de Fixação do Látex | pt_BR |
| DeCS | Proteínas de protozoários | pt_BR |
| DeCS | Meia-Idade | pt_BR |
| DeCS | Reprodutibilidade dos testes | pt_BR |
| DeCS | Sensibilidade e Especificidade | pt_BR |
| DeCS | Adulto Jovem | pt_BR |
| xmlui.metadata.dc.subject.ods | 05 Igualdade de gênero | |
