| Author | Pinto, Larissa G. | |
| Author | Talbot, Jhimmy | |
| Author | Peres, Raphael S. | |
| Author | Franca, Rafael F. | |
| Author | Ferreira, Sérgio H. | |
| Author | Ryffel, Bernhard | |
| Author | Aves-Filho, José Carlos F. | |
| Author | Figueiredo, Florêncio | |
| Author | Cunha, Thiago M. | |
| Author | Cunha, Fernando Q. | |
| Access date | 2017-09-20T19:38:49Z | |
| Available date | 2017-09-20T19:38:49Z | |
| Document date | 2015 | |
| Citation | PINTO, L. G. et al. Joint production of IL-22 participates in the initial phase of antigen-induced arthritis through IL-1β production. Arthritis Research & Therapy, v. 17, p. 235, 2 set. 2015. | pt_BR |
| ISSN | 1478-6362 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/21078 | |
| Language | por | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Artrite Experimental | pt_BR |
| Subject in Portuguese | Interleucina-1beta | pt_BR |
| Subject in Portuguese | Interleucinas | pt_BR |
| Subject in Portuguese | Articulação do Joelho | pt_BR |
| Title | Joint production of IL-22 participates in the initial phase of antigen-induced arthritis through IL-1β production | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1186/s13075-015-0759-2 | |
| Abstract | Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by neutrophil articular infiltration, joint pain and the progressive destruction of cartilage and bone. IL-22 is a key effector molecule that plays a critical role in autoimmune diseases. However, the function of IL-22 in the pathogenesis of RA remains controversial. In this study, we investigated the role of IL-22 in the early phase of antigen-induced arthritis (AIA) in mice. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil | pt_BR |
| Subject | Animals | pt_BR |
| Subject | Antigens | pt_BR |
| Subject | Apoptosis Regulatory Proteins | pt_BR |
| Subject | Arthralgia | pt_BR |
| Subject | Arthritis, Experimental | pt_BR |
| Subject | Cell Movement | pt_BR |
| Subject | Enzyme-Linked Immunosorbent Assay | pt_BR |
| Subject | Enzyme-Linked Immunosorbent Assay | pt_BR |
| Subject | Gene Expression | pt_BR |
| Subject | Interleukin-1beta | pt_BR |
| Subject | Knee Joint | pt_BR |
| Subject | Mice, Inbred C57BL | pt_BR |
| Subject | Mice, Knockout | pt_BR |
| Subject | Neutrophils | pt_BR |
| Subject | Reverse Transcriptase Polymerase Chain Reaction | pt_BR |
| Subject | Synovial Membrane | pt_BR |
| Subject | Synovitis | pt_BR |
| Subject | Zymosan | pt_BR |
| DeCS | Artrite Experimental | pt_BR |
| DeCS | genética | pt_BR |
| DeCS | metabolismo | pt_BR |
| DeCS | imunologia | pt_BR |
| DeCS | Interleucina-1beta | pt_BR |
| DeCS | Interleucinas | pt_BR |
| DeCS | Animais | pt_BR |
| DeCS | Antígenos | pt_BR |
| DeCS | Proteínas Reguladoras de Apoptose | pt_BR |
| DeCS | Arthralgia | pt_BR |
| DeCS | Movimento Celular | pt_BR |
| DeCS | Ensaio de Imunoadsorção Enzimática | pt_BR |
| DeCS | Expressão Gênica | pt_BR |
| DeCS | Articulação do Joelho | pt_BR |
| DeCS | Camundongos Endogâmicos C57BL | pt_BR |
| DeCS | Camundongos Knockout | pt_BR |
| DeCS | Neutrófilos | pt_BR |
| DeCS | Reação em Cadeia da Polimerase Via Transcriptase Reversa | pt_BR |
| DeCS | Membrana Sinovial | pt_BR |
| DeCS | Sinovite | pt_BR |
| DeCS | Zimosan | pt_BR |
