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A MULTICENTRE RANDOMIZED CONTROLLED TRIAL OF THE EFFICACY AND SAFETY OF SINGLE-DOSE PRAZIQUANTEL AT 40 MG/KG VS. 60 MG/KG FOR TREATING INTESTINAL SCHISTOSOMIASIS IN THE PHILIPPINES, MAURITANIA, TANZANIA AND BRAZIL
Olliaro, Piero L. et al. | Date Issued: 2011
Author
Olliaro, Piero L.
Vaillant, Michel T.
Belizario, Vincente J.
Lwambo, Nicholas J. S.
Ouldabdallahi, Mohamed
Pieri, Otavio S.
Amarillo, Maria L.
Kaatano, Godfrey M.
Diaw, Mamadou
Domingues, Analucia C.
Favre, Tereza C.
Lapujade, Olivier
Alves, Fabiana
Chitsulo, Lester
Affilliation
UNICEF/UNDP/World Bank/WHO Special Programme on Research and Training in Tropical Diseases (TDR). World Health Organization, Geneva, Switzerland.
Methodology and Statistical Unit, Center for Health Studies. Centre de Recherche – Sante´ . Strassen, Luxembourg.
National Institutes of Health. University of the Philippines Malaria. Manila, Philippines.
National Institute for Medical Research. Mwanza Medical Research Centre. Mwanza, Tanzania.
Nutrition et Actes Médicaux. Institut National de Recherches en Santé Publique (INRSP). Nouakchott, Mauritania.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Eco-Epidemiologia e Controle da Esquistossomose e Geohelmintoses. Rio de Janeiro, RJ. Brasil.
University of the Philippines. College of Medecine. Department of Clinical Epidemiology. Manilla, Philippines.
National Institute for Medical Research. Mwanza Medical Research Centre. Mwanza, Tanzania.
Ministére de la Santé /P.E.V.. Nouakchott, Mauritania.
Universidade Federal de Pernambuco. Centro de Ciências da Saúde. Departamento de Medicina Clínica. Recife, PE, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Eco-Epidemiologia e Controle da Esquistossomose e Geohelmintoses. Rio de Janeiro, RJ. Brasil.
UNICEF/UNDP/World Bank/WHO Special Programme on Research and Training in Tropical Diseases (TDR). World Health Organization, Geneva, Switzerland.
Latin America Regional Office, Drugs for Neglected Diseases Initiative. Rio de Janeiro, RJ, Brasil.
Abstract
Praziquantel at 40 mg/kg in a single dose is the WHO recommended treatment for all forms of schistosomiasis, but 60 mg/kg is also deployed nationally.
Keywords in Portuguese
Esquistossomose
Tratamento
Praziquantel
 
Keywords
intestinal schistosomiasis
Praziquantel
treatment
 
Publisher
Public Library of Science
Citation
OLLIARO, Piero L. et al. A Multicentre Randomized Controlled Trial of the Efficacy and Safety of Single-Dose Praziquantel at 40 mg/kg vs. 60 mg/kg for Treating Intestinal Schistosomiasis in the Philippines, Mauritania, Tanzania and Brazil. PLoS Negl Trop Dis 5(6): e1165, 15p, June 2011.
DOI
10.1371/journal.pntd.0001165
ISSN
1935-2727