| Author | Aguirre-Obando, Oscar Alexander | |
| Author | Martins, Ademir Jesus | |
| Author | Silva, Mário Antônio Navarro | |
| Access date | 2017-10-10T14:11:47Z | |
| Available date | 2017-10-10T14:11:47Z | |
| Document date | 2017 | |
| Citation | AGUIRRE-OBANDO, Oscar Alexander; MARTINS, Ademir Jesus; SILVA, Mário Antônio Navarro. First report of the Phe1534Cys kdr mutation in natural populations of Aedes albopictus from Brazil. Parasites & Vectors, v10:160, 10p, 2017. | pt_BR |
| ISSN | 1756-3305 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/22815 | |
| Language | eng | pt_BR |
| Publisher | BioMed Central | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Dengue | pt_BR |
| Subject in Portuguese | Zika | pt_BR |
| Subject in Portuguese | Chikungunya | pt_BR |
| Subject in Portuguese | Controle de vetores | pt_BR |
| Subject in Portuguese | Resistência à piretróide | pt_BR |
| Subject in Portuguese | Canais de Sódio | pt_BR |
| Subject in Portuguese | Alelos | pt_BR |
| Subject in Portuguese | Reação em Cadeia da Polimerase | pt_BR |
| Title | First report of the Phe1534Cys kdr mutation in natural populations of Aedes albopictus from Brazil | pt_BR |
| Type | Article | |
| DOI | 10.1186/s13071-017-2089-5 | |
| Abstract | Knockdown resistance (kdr), caused by alterations in the voltage-gated sodium channel (NaV), is one of the mechanisms responsible for pyrethroid (PY) resistance. In the Asian tiger mosquito, Aedes albopictus, at least four different mutations were described in the IIIS6 NaV segment in populations from Asia, North America and Europe. In contrast, in Aedes aegypti at least 12 non-synonymous mutations have been reported at nine different codons, mostly in the IIS6 and IIIS6 NaV segments. The Phe1534Cys kdr mutation in the IIIS6 NaV segment is the most prevalent in populations of Ae. aegypti worldwide, also found in Ae. albopictus from Singapore. Herein, we investigated the DNA diversity corresponding to the IIS6 and IIIS6 NaV segments in natural populations of Ae. albopictus from Brazil. | pt_BR |
| Affilliation | Universidade Federal do Paraná. Departamento de Zoologia. Setor de Ciências Biológicas. Laboratório de Entomologia Médica e Veterinária. Curitiba, Paraná, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Controle de Artrópodes Vetores. Rio de Janeiro, RJ. Brasil / Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Paraná. Departamento de Zoologia. Setor de Ciências Biológicas. Laboratório de Entomologia Médica e Veterinária. Curitiba, Paraná, Brasil. | pt_BR |
| Subject | Allele-specific PCR | pt_BR |
| Subject | Chikungunya | pt_BR |
| Subject | Dengue | pt_BR |
| Subject | Pyrethroid resistance | pt_BR |
| Subject | Vector control | pt_BR |
| Subject | Voltage-gated-sodium channel | pt_BR |
| Subject | Zika | pt_BR |
