| Author | Affonso, Raphael | |
| Author | Lima, Josélia | |
| Author | Lessa, Bruno | |
| Author | Caetano, João | |
| Author | Obara, Marcos | |
| Author | Nóbrega, Andrea | |
| Author | Nepominova, Eugenie | |
| Author | Musilek, Kamil | |
| Author | Kuca, Kamil | |
| Author | Slana, Gláucia Barbosa Candido Alves | |
| Author | França, Tanos | |
| Access date | 2017-10-10T14:37:23Z | |
| Available date | 2017-10-10T14:37:23Z | |
| Document date | 2017 | |
| Citation | AFFONSO, Raphael. Quantification through TLC-Densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian cloves. Biomed Chromatogr, Sep 2017. | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/22816 | |
| Language | por | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Syzygium Aromaticum L. | pt_BR |
| Subject in Portuguese | Repelente de Insetos | pt_BR |
| Subject in Portuguese | Eugenol | pt_BR |
| Subject in Portuguese | Anti-Colinesterase | pt_BR |
| Subject in Portuguese | Aedes Aegypti | pt_BR |
| Title | Quantification through TLC-Densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian cloves | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.1002/bmc.4096 | |
| Abstract | The rise of mosquito’s transmitted diseases, like dengue, zika and chikungunya in Brazil in the last years has increased the concerns on protection against mosquito’s bites. However, the prohibitive prices of the commercially available repellents for the majority of the Brazilian population, has provoked a search for cheaper solutions, like the use of the homemade ethanolic extract of Indian clove (Syzygium aromaticum L.) as repellent, which has been reported as quite efficient by the local press. In order to verify this, we performed
here, the quantification of the main components of this extract through high-performance thin-layer chromatography (HPTLC)-densitometry and evaluated its efficiency as repellent, as well as the acetylcholinesterase (AChE) inhibition capacity. Our results have proved HPTLC-densitometry as an efficient and appropriate method for this quantification and confirmed the repellency activity as well as its capacity of AChE inhibition. | pt_BR |
| Affilliation | Instituto Militar de Engenharia. Modelagem Aplicada à Defesa Química e Biológica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Instituto Militar de Engenharia. Modelagem Aplicada à Defesa Química e Biológica. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Plataforma Agroecológica de Fitomedicina. Laboratório de Química da Biodiversidade. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Anhanguera College of Brasília. Brasília, Brasil. | pt_BR |
| Affilliation | Universidade de Brasília. Núcleo de medicina tropical. Brasília, Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Plataforma Agroecológica de Fitomedicina. Laboratório de Química da Biodiversidade. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Hospital Universitário Hradec Kralove. Biomedical Research Center. Hradec Kralove, República Tcheca. | pt_BR |
| Affilliation | Hospital Universitário Hradec Kralove. Biomedical Research Center. Hradec Kralove, República Tcheca. | pt_BR |
| Affilliation | Hospital Universitário Hradec Kralove. Biomedical Research Center. Hradec Kralove, República Tcheca / Universidade da Defesa. Faculdade de Ciências da Saúde Militares. Departamento de Toxicologia e Farmácia Militar. Hradec Kralove, República Tcheca | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Plataforma Agroecológica de Fitomedicina. Laboratório de Química da Biodiversidade. Rio de Janeiro, RJ, Brasil / Instituto Nacional de Propriedade Intelectual. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Instituto Militar de Engenharia. Modelagem Aplicada à Defesa Química e Biológica. Rio de Janeiro, RJ, Brasil / Universidade de Hradec Kralove. Faculdade de Informática e Gestão. Centro para Pesquisa Básica e Aplicada. Hradec Kralove, República Tcheca. | pt_BR |
| Subject | Syzygium Aromaticum L. | pt_BR |
| Subject | Insect Repellent | pt_BR |
| Subject | Eugenol | pt_BR |
| Subject | Anticholinesterase | pt_BR |
| Subject | Aedes Aegypti | pt_BR |
