Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/22816
Title: Quantification through TLC-Densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian cloves
Authors: Affonso, Raphael
Lima, Josélia
Lessa, Bruno
Caetano, João
Obara, Marcos
Nóbrega, Andrea
Nepominova, Eugenie
Musilek, Kamil
Kuca, Kamil
Slana, Gláucia Barbosa Candido Alves
França, Tanos
Affilliation: Instituto Militar de Engenharia. Modelagem Aplicada à Defesa Química e Biológica. Rio de Janeiro, RJ, Brasil.
Instituto Militar de Engenharia. Modelagem Aplicada à Defesa Química e Biológica. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Plataforma Agroecológica de Fitomedicina. Laboratório de Química da Biodiversidade. Rio de Janeiro, RJ, Brasil.
Anhanguera College of Brasília. Brasília, Brasil.
Universidade de Brasília. Núcleo de medicina tropical. Brasília, Brasil.
Fundação Oswaldo Cruz. Plataforma Agroecológica de Fitomedicina. Laboratório de Química da Biodiversidade. Rio de Janeiro, RJ, Brasil.
Hospital Universitário Hradec Kralove. Biomedical Research Center. Hradec Kralove, República Tcheca.
Hospital Universitário Hradec Kralove. Biomedical Research Center. Hradec Kralove, República Tcheca.
Hospital Universitário Hradec Kralove. Biomedical Research Center. Hradec Kralove, República Tcheca / Universidade da Defesa. Faculdade de Ciências da Saúde Militares. Departamento de Toxicologia e Farmácia Militar. Hradec Kralove, República Tcheca
Fundação Oswaldo Cruz. Plataforma Agroecológica de Fitomedicina. Laboratório de Química da Biodiversidade. Rio de Janeiro, RJ, Brasil / Instituto Nacional de Propriedade Intelectual. Rio de Janeiro, RJ, Brasil.
Instituto Militar de Engenharia. Modelagem Aplicada à Defesa Química e Biológica. Rio de Janeiro, RJ, Brasil / Universidade de Hradec Kralove. Faculdade de Informática e Gestão. Centro para Pesquisa Básica e Aplicada. Hradec Kralove, República Tcheca.
Abstract: The rise of mosquito’s transmitted diseases, like dengue, zika and chikungunya in Brazil in the last years has increased the concerns on protection against mosquito’s bites. However, the prohibitive prices of the commercially available repellents for the majority of the Brazilian population, has provoked a search for cheaper solutions, like the use of the homemade ethanolic extract of Indian clove (Syzygium aromaticum L.) as repellent, which has been reported as quite efficient by the local press. In order to verify this, we performed here, the quantification of the main components of this extract through high-performance thin-layer chromatography (HPTLC)-densitometry and evaluated its efficiency as repellent, as well as the acetylcholinesterase (AChE) inhibition capacity. Our results have proved HPTLC-densitometry as an efficient and appropriate method for this quantification and confirmed the repellency activity as well as its capacity of AChE inhibition.
Keywords: Syzygium Aromaticum L.
Insect Repellent
Eugenol
Anticholinesterase
Aedes Aegypti
keywords: Syzygium Aromaticum L.
Repelente de Insetos
Eugenol
Anti-Colinesterase
Aedes Aegypti
Issue Date: 2017
Citation: AFFONSO, Raphael. Quantification through TLC-Densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian cloves. Biomed Chromatogr, Sep 2017.
DOI: 10.1002/bmc.4096
Copyright: open access
Appears in Collections:Farmanguinhos - Artigos de Periódicos

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