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RECOMMENDATIONS OF THE BRAZILIAN SOCIETY OF RHEUMATOLOGY FOR THE DIAGNOSIS AND TREATMENT OF CHIKUNGUNYA FEVER: PART 2 - TREATMENT
Author
Marques, Claudia Diniz Lopes
Duarte, Angela Luzia Branco Pinto
Ranzolin, Aline
Dantas, Andrea Tavares
Cavalcanti, Nara Gualberto
Gonçalves, Rafaela Silva Guimarães
Rocha Junior, Laurindo Ferreira da
Valadares, Lilian David de Azevedo
Melo, Ana Karla Guedes de
Freire, Eutilia Andrade Medeiros
Bezerra Neto, Roberto Teixeira Francisco Alves
Medeiros, Marta Maria das Chagas
Carvalho, Jozélio Freire de
Santos, Mario Sergio F.
Océa, Regina Adalva de L. Couto
Levy, Roger A.
Andrade, Carlos Augusto Ferreira de
Pinheiro, Geraldo da Rocha Castelar
Abreu, Mirhelen Mendes
Verztman, José Fernando
Merenlender, Selma
Ribeiro, Sandra Lucia Euzebio
Costa, Izaias Pereira da
Pileggi, Gecilmara
Trevisani, Virginia Fernandes Moça
Lopes, Max Igor Banks
Brito, Carlos
Figueiredo, Eduardo
Queiroga, Fabio
Feitosa, Tiago
Tenório, Angélica da Silva
Siqueira, Gisela Rocha de
Paiva, Renata
Vasconcelos, José Tupinambá Sousa
Christopoulos, Georges
Duarte, Angela Luzia Branco Pinto
Ranzolin, Aline
Dantas, Andrea Tavares
Cavalcanti, Nara Gualberto
Gonçalves, Rafaela Silva Guimarães
Rocha Junior, Laurindo Ferreira da
Valadares, Lilian David de Azevedo
Melo, Ana Karla Guedes de
Freire, Eutilia Andrade Medeiros
Bezerra Neto, Roberto Teixeira Francisco Alves
Medeiros, Marta Maria das Chagas
Carvalho, Jozélio Freire de
Santos, Mario Sergio F.
Océa, Regina Adalva de L. Couto
Levy, Roger A.
Andrade, Carlos Augusto Ferreira de
Pinheiro, Geraldo da Rocha Castelar
Abreu, Mirhelen Mendes
Verztman, José Fernando
Merenlender, Selma
Ribeiro, Sandra Lucia Euzebio
Costa, Izaias Pereira da
Pileggi, Gecilmara
Trevisani, Virginia Fernandes Moça
Lopes, Max Igor Banks
Brito, Carlos
Figueiredo, Eduardo
Queiroga, Fabio
Feitosa, Tiago
Tenório, Angélica da Silva
Siqueira, Gisela Rocha de
Paiva, Renata
Vasconcelos, José Tupinambá Sousa
Christopoulos, Georges
Affilliation
Multipla - ver em Notas
Abstract
Chikungunya fever has become an important public health problem in countries where epidemics occur because half of the cases progress to chronic, persistent and debilitating arthritis. Literature data on specific therapies at the various phases of arthropathy caused by chikungunya virus (CHIKV) infection are limited, lacking quality randomized trials assessing the efficacies of different therapies. There are a few studies on the treatment of musculoskeletal manifestations of chikungunya fever, but these studies have important methodological limitations. The data currently available preclude conclusions favorable or contrary to specific therapies, or an adequate comparison between the different drugs used. The objective of this study was to develop recommendations for the treatment of chikungunya fever in Brazil. A literature review was performed via evidence-based selection of articles in the databases Medline, SciELO, PubMed and Embase and conference proceedings abstracts, in addition to expert opinions to support decision-making in defining recommendations. The Delphi method was used to define the degrees of agreement in 2 face-to-face meetings and several online voting rounds. This study is part 2 of the Recommendations of the Brazilian Society of Rheumatology (Sociedade Brasileira de Reumatologia - SBR) for the Diagnosis and Treatment of chikungunya fever and specifically addresses treatment.
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