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DOUBLE IMPACT: NATURAL MOLLUSCICIDE FOR SCHISTOSOMIASIS VECTOR CONTROL ALSO IMPEDES DEVELOPMENT OF SCHISTOSOMA MANSONI CERCARIAE INTO ADULT PARASITES
Augusto, Ronaldo de Carvalho et al. | Date Issued: 2017
Author
Augusto, Ronaldo de Carvalho
Tetreau, Guillaume
Chan, Philippe
Walet-Balieu, Marie-Laure
Silva, Clélia Christina Mello
Santos, Cláudia Portes
Grunau, Christoph
Affilliation
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da saúde Ambiental. Rio de Janeiro, RJ. Brasil / Univ. Perpignan Via Domitia. Univ. Montpellier. Perpigna, France.
Univ. Perpignan Via Domitia. Univ. Montpellier. Perpigna, France.
University of Rouen. Institute for Research and Innovation in Biomedicine. PISSARO Proteomic Platform. Rouen, France.
University of Rouen. Institute for Research and Innovation in Biomedicine. PISSARO Proteomic Platform. Rouen, France.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da saúde Ambiental. Rio de Janeiro, RJ. Brasil
Univ. Perpignan Via Domitia. Univ. Montpellier. Perpigna, France.
Abstract
Schistosomiasis has been reported in 78 endemic countries and affects 240 million people worldwide. The digenetic parasite Schistosoma mansoni needs fresh water to compete its life cycle. There, it is susceptible to soluble compounds that can affect directly and/or indirectly the parasite's biology. The cercariae stage is one of the key points in which the parasite is vulnerable to different soluble compounds that can significantly alter the parasite's life cycle. Molluscicides are recommended by the World Health Organization for the control of schistosomiasis transmission and Euphorbia milii latex is effective against snails intermediate hosts.
Keywords in Portuguese
Esquistossomose
Schistosoma mansoni
Controle de vetores
Parasitos
Schistosoma mansoni
 
Keywords
schistosomiasis
vector control
Schistosoma mansoni
molluscicide
 
Publisher
Public Library of Science
Citation
AUGUSTO, Ronaldo de Carvalho; et al. Double impact: natural molluscicide for schistosomiasis vector control also impedes development of Schistosoma mansoni cercariae into adult parasites. PLoS Negl Trop Dis, v.11, n.7, e0005789., July 2017.
DOI
10.1371/journal.pntd.0005789
ISSN
1935-2727