Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/23186
Title: Cross-Sectional Study to Determine the Prevalence of Hepatitis B and C Virus Infection in High Risk Groups in the Northeast Region of Brazil
Authors: Barbosa, Jakeline Ribeiro
Bezerra, Cristianne Sousa
Costa, Filipe Anibal Carvalho
Azevedo, Carolina Pimentel de
Flores, Geane Lopes
Colares, Jeová Keny Baima
Lima, Danielle Malta
Lampe, Elisabeth
Villar, Lívia Melo
Affilliation: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ. Brasil / Universidade Federal do Ceará. Programa de Pós-Graduação em Patologia. Fortaleza, CE, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ. Brasil / Universidade Federal do Ceará. Programa de Pós-Graduação em Patologia. Fortaleza, CE, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Epidemiologia e Sistemática Molecular. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ. Brasil.
Universidade Federal do Ceará. Programa de Pós-Graduação em Patologia. Fortaleza, CE, Brasil / Universidade de Fortaleza. Programa de Pós-Graduação em Ciências Médicas. Fortaleza, CE, Brasil.
Universidade Federal do Ceará. Programa de Pós-Graduação em Patologia. Fortaleza, CE, Brasil / Universidade de Fortaleza. Programa de Pós-Graduação em Ciências Médicas. Fortaleza, CE, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ. Brasil.
Abstract: Background: HBV (Hepatitis B Virus) and HCV (Hepatitis C Virus) infections are more prevalent in vulnerable populations than the general population. The objective of this study was to investigate the prevalence of HBV and HCV infection in HIV-positive patients (GI), chronic renal failure (CRF) patients (GII) and coagulation disorder individuals (GIII). Methods: A cross-sectional study was conducted from June 2014 to March 2015. Serum samples were tested for markers of hepatitis B and C by enzyme-linked immunosorbent assay (ELISA). Sociodemographic, epidemiological, clinical and laboratory data and accompanying statistical analyses were performed using Epi Info™ 7. Results: A total of 348 individuals were recruited, i.e., 154 HIV-positive, 143 CRF and 51 coagulopathy patients. Among them, more than 66% were men, and the predominant age group was 26-35 years in GI and 56-65 years in GIII. Most patients had more than 8 years of education (66.2% in GI, 60.6% in GIII and 46.1% in GII), with a family income between 100-400 dollars in more than 48% of patients. The prevalence of the HBsAg marker was 3.9%, 7% and 3.9%, total anti-HBc was 28.6%, 55.9% and 31.4%, and anti-HCV was 1.3%, 12.6% and 47% for GI, GII and GIII, respectively. However, the prevalence of anti-HBs was greater than 70% in all groups. Conclusions: This study shows a high prevalence of HBV and HCV among specific groups compared to the general population. Factors such as age, income, number of sexual partners, sexually transmitted disease burden, blood transfusion history or blood products and blood transfusions before 1994 were associated with a higher prevalence for these infections.
Keywords: prevalence
hepatitis B virus
hepatitis C virus
human immunodeficiency virus 1
haemodialysis
coagulopathy
keywords: Vírus da Hepatite B
Coagulação Intravascular Disseminada
Vírus da Hepaitie C
Prevalência
HIV-1
Hemodiálise
Issue Date: 2017
Publisher: MDPI
Citation: BARBOSA, Jakeline Ribeiro; et al. Cross-Sectional Study to Determine the Prevalence of Hepatitis B and C Virus Infection in High Risk Groups in the Northeast Region of Brazil.Int. J. Environ. Res. Public Health, v.14, n.793, 12p, July 2017.
DOI: 10.3390/ijerph14070793
ISSN: 1661-7827
Copyright: open access
Appears in Collections:IOC - Artigos de Periódicos

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