| Author | Paploski, Igor Adolfo Dexheimer | |
| Author | Souza, Raquel Lima | |
| Author | Tauro, Laura Beatriz | |
| Author | Cardoso, Cristiane Wanderley | |
| Author | Mugabe, Vánio André | |
| Author | Alves, Anna Beatriz Pereira Simões | |
| Author | Gomes, Joice de Jesus | |
| Author | Kikuti, Mariana | |
| Author | Campos, Gubio Soares | |
| Author | Sardi, Sílvia | |
| Author | Weaver, Scott C | |
| Author | Reis, Mitermayer Galvão dos | |
| Author | Kitron, Uriel | |
| Author | Ribeiro, Guilherme de Sousa | |
| Access date | 2017-11-27T13:55:32Z | |
| Available date | 2017-11-27T13:55:32Z | |
| Document date | 2017 | |
| Citation | PAPLOSKI, I. A. D. et al. Epizootic outbreak of yellow fever virus and risk for human disease in Salvador, Brazil. Annals of Internal Medicine, 2017. | pt_BR |
| ISSN | 0003-4819 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/23365 | |
| Sponsorship | Brazilian National Council for Scientific and Technological Development (grants 400830/2013-2 and 440891/
2016-7, the Brazilian Coordination for the Improvement of Higher Education (grant 440891/2016-7, the Bahia Foundation for Research Support (grant PET0022/2016), the University of Texas Medical Branch Institute for Human Infections and Immunity, and National Institutes of Health (grant R24AI120942). | pt_BR |
| Language | eng | pt_BR |
| Publisher | American College of Physicians | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Febre Amarela | pt_BR |
| Subject in Portuguese | Virus | pt_BR |
| Subject in Portuguese | Investigação de surto de doenças | pt_BR |
| Subject in Portuguese | Transmisão | pt_BR |
| Subject in Portuguese | Aedes aegypti | pt_BR |
| Subject in Portuguese | Vacinação | pt_BR |
| Subject in Portuguese | Óbito | pt_BR |
| Subject in Portuguese | Fatores de risco | pt_BR |
| Subject in Portuguese | Humanos | pt_BR |
| Subject in Portuguese | Brasil | pt_BR |
| Title | Epizootic Outbreak of Yellow Fever Virus and Risk for Human Disease in Salvador, Brazil | pt_BR |
| Type | Article | pt_BR |
| DOI | 10.7326/M17-1949 | |
| Abstract | Background: Yellow fever virus (YFV) is an RNA virus
maintained in an enzootic, sylvatic cycle involving nonhuman
primates (NHPs) and sylvatic mosquito vectors primarily of the
genus Haemagogus and Sabethes. Transmission occasionally
spills over to humans entering forested regions. In the Americas,
urban transmission of YFV to humans has not occurred
since the mid-1900s because of vaccination and near-elimination
of the anthropophilic Aedes aegypti, the urban vector (1). However,
concerns about reemergence of urban YFV have recently
increased because of the reappearance and rapid spread of
A aegypti in the urban environment. Furthermore, immunization
coverage for YFV is insufficient because vaccination is
generally indicated only for higher-risk populations, such as
those living in or travelling to areas with sylvatic transmission.
Objective: To investigate the 2017 epizootic outbreak of
YFV and the risk for human disease in Salvador, Brazil.
Methods and Findings: Since November 2016, deaths of
NHPs due to YFV in Brazil have been reported in the state of
Sa˜o Paulo. Beginning in December 2016, human cases were
also reported in the states of Sa˜o Paulo and Minas Gerais. By
the end of May 2017, the YFV outbreak in humans had spread to 9 Brazilian states, with more than 130 municipalities reporting
confirmed cases (Appendix Figure 1, available at www
.annals.org), all deemed of sylvatic origin (rather than via urban
A aegypti transmission). | pt_BR |
| Affilliation | Universidade Federal da Bahia. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Secretaria Municipal de Saúde de Salvador. Salvador, BA, Brasil | pt_BR |
| Affilliation | Universidade Federal da Bahia. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Universidade Federal da Bahia. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Universidade Federal da Bahia. Salvador, BA, Brasil | pt_BR |
| Affilliation | Universidade Federal da Bahia. Salvador, BA, Brasil | pt_BR |
| Affilliation | University of Texas Medical Branch. Galveston, Texas | pt_BR |
| Affilliation | Universidade Federal da Bahia. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Emory University. Atlanta, Georgia | pt_BR |
| Affilliation | Universidade Federal da Bahia. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Subject | Yellow Fever | pt_BR |
| Subject | Virus | pt_BR |
| Subject | Disease outbreak investigation | pt_BR |
| Subject | Transmission | pt_BR |
| Subject | Aedes aegypti | pt_BR |
| Subject | Vaccination | pt_BR |
| Subject | Death | pt_BR |
| Subject | Risk factors | pt_BR |
| Subject | Humans | pt_BR |
| Subject | Brazil | pt_BR |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
