| Author | Morais, Isa Rita Brito de | |
| Author | Guerreiro, Marcos Lázaro da Silva | |
| Author | Patriota, G. S. Q | |
| Author | Santos, Viviane Corrêa | |
| Author | Macedo, Andrea Mara | |
| Author | Andrade, Sonia Gumes | |
| Access date | 2017-12-07T17:45:20Z | |
| Available date | 2017-12-07T17:45:20Z | |
| Document date | 2012 | |
| Citation | MORAIS, I. R. B. et al. Biological and molecular characterization of clonal populations of Trypanosoma cruzi strains: 21SF – Biodeme Type II and Colombian strain – Biodeme Type III, isolated from infected mice, treated with Benznidazole and not cured. In: CONGRESSO INTERNACIONAL DE MEDICINA TROPICAL E MALÁRIA, 18 e CONGRESSO DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 48., 2012, Rio de Janeiro. Resumos... Rio de Janeiro: Sociedade Brasileira de Medicina Tropical, 2012. | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/23557 | |
| Language | eng | pt_BR |
| Publisher | Sociedade Brasileira de Medicina Tropical | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Trypanosoma cruzi | pt_BR |
| Subject in Portuguese | Quimioterápicos | pt_BR |
| Subject in Portuguese | Drogas | pt_BR |
| Subject in Portuguese | Camundogos | pt_BR |
| Subject in Portuguese | Animais | pt_BR |
| Title | Biological and molecular characterization of clonal populations of Trypanosoma cruzi strains: 21SF – Biodeme Type II and Colombian strain – Biodeme Type III, isolated from infected mice, treated with Benznidazole and not cured | pt_BR |
| Type | Papers presented at events | pt_BR |
| Abstract | Introduction: Different strains and clones of Trypanosoma cruzi present different degrees of
susceptibility to treatment with chemotherapic drugs. Several studies have been developed to evaluate
the response to different drugs concerning the strains prototypes of Biodemes Types I, II and III
according to the biological characterization. Results have shown that the strains prototypes of the
Biodeme Type I (Y and Peruvian strains) disclosed a high susceptibility to treatment with Benznidazole
and Nifurtimox; strains of the Biodeme Type II (prototype: the 21SF strain) showed a medium
susceptibility; the strains of the Biodeme Type III (Colombian strain) were highly resistant | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Chagas Experimental Autoimunidade e Imunologia Celular. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Chagas Experimental Autoimunidade e Imunologia Celular. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Chagas Experimental Autoimunidade e Imunologia Celular. Salvador, BA, Brasil | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Departamento de Bioquimica e IMunologia. Belo Horizonte, MG, Brazil | pt_BR |
| Affilliation | Universidade Federal de Minas Gerais. Departamento de Bioquimica e IMunologia. Belo Horizonte, MG, Brazil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Chagas Experimental Autoimunidade e Imunologia Celular. Salvador, BA, Brasil | pt_BR |
| Subject | Trypanosoma cruzi | pt_BR |
| Subject | Chemotherapic | pt_BR |
| Subject | Drugs | pt_BR |
| Subject | Mice | pt_BR |
| Subject | Animals | pt_BR |
