Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/23558
Title: Immunopathological response in mice with triple infection with Trypanosoma cruzi strains of different Biodemes submitted to treatment with immunossupressor drugs
Authors: Magalhães, Lorena dos Anjos
Souza Junior, A. F
Guerreiro, Marcos Lázaro da Silva
Andrade, Sonia Gumes
Affilliation: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Chagas Experimental Autoimunidade e Imunologia Celular. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Chagas Experimental Autoimunidade e Imunologia Celular. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Chagas Experimental Autoimunidade e Imunologia Celular. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Chagas Experimental Autoimunidade e Imunologia Celular. Salvador, BA, Brasil
Abstract: Introduction: An important factor that contributes to the severity of Chagas disease in people living in endemic areas is the occurrence of multiple infections with Trypanosoma cruzi. Experimental studies have shown the increased morbidity due to successive reinfections with different strains, with the possibility of to evaluate the influence of multiple infections upon the tissue lesions. Multiple infections could also influence an activation of the disease in patients with HIV infection (AIDs) or immunosuppressed in cases of organs transplantation. In such cases, a reactivation of virulent strains could occur with aggravation of the disease. Objective: to evaluate the immunopathological response in mice triple infected with different T. cruzi strains and treated with immunosuppressor drugs.
Keywords: Trypanosoma cruzi
Chagas disease
HIV infection
Mice
keywords: Trypanosoma cruzi
Doença de Chagas
Infecções por HIV
Camundogos
Issue Date: 2012
Publisher: Sociedade Brasileira de Medicina Tropical
Citation: MAGALHÃES, L. A. et al. Immunopathological response in mice with triple infection with Trypanosoma cruzi strains of different Biodemes submitted to treatment with immunossupressor drugs. In: CONGRESSO INTERNACIONAL DE MEDICINA TROPICAL E MALÁRIA, 18 e CONGRESSO DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 48., 2012, Rio de Janeiro. Resumos... Rio de Janeiro: Sociedade Brasileira de Medicina Tropical, 2012.
Copyright: open access
Appears in Collections:BA - IGM - Trabalhos Apresentados em Eventos

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