| Author | Meira, Cássio Santana | |
| Author | Guimarães, Elisalva Teixeira | |
| Author | Bastos, Tanira Matutino | |
| Author | Castro, Murilo Fagundes de | |
| Author | Moreira, Diogo Rodrigo de Magalhães | |
| Author | Santos Filho, J. M. dos | |
| Author | Soares, Milena Botelho Pereira | |
| Access date | 2017-12-11T13:17:14Z | |
| Available date | 2017-12-11T13:17:14Z | |
| Document date | 2012 | |
| Citation | MEIRA, C. S. et al. In vitro and in vivo evaluation anti-Trypanosoma cruzi activity of N-acylhydrazones oxadiazoles. In: CONGRESSO INTERNACIONAL DE MEDICINA TROPICAL E MALÁRIA, 18 e CONGRESSO DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 48., 2012, Rio de Janeiro. Resumos... Rio de Janeiro: Sociedade Brasileira de Medicina Tropical, 2012. | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/23597 | |
| Language | eng | pt_BR |
| Publisher | Sociedade Brasileira de Medicina Tropical | pt_BR |
| Rights | open access | pt_BR |
| Subject in Portuguese | Trypanosoma cruzi | pt_BR |
| Subject in Portuguese | Doença de Chagas | pt_BR |
| Subject in Portuguese | Saude publica | pt_BR |
| Subject in Portuguese | Tratamento | pt_BR |
| Subject in Portuguese | Microscopia eletrônica | pt_BR |
| Title | In vitro and in vivo evaluation anti-Trypanosoma cruzi activity of N-acylhydrazones oxadiazoles | pt_BR |
| Type | Papers presented at events | pt_BR |
| Abstract | Chagas disease, or American trypanosomiasis, is caused by the flagellate protozoan Trypanosoma cruzi.
One century after its discovery, Chagas disease still remains a major health problem in Latin America.
Treatment is based on benznidazole that have toxic effects and limited efficacy. Therefore, new
chemotherapeutic agents are urgently needed. In this context, the effects of sixteen N-acylhydrazone
oxadiazoles were evaluated as potential candidates for anti-T. cruzi agents | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Federal University of Pernambuco. Department of Pharmaceutical Sciences. Recife, PE, Brazil | pt_BR |
| Affilliation | Federal University of Pernambuco. Department of Pharmaceutical Sciences. Recife, PE, Brazil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Hospital São Rafael. Center of Biotechnology and Cell Therapy. Salvador, BA, Brazil | pt_BR |
| Subject | Trypanosoma cruzi | pt_BR |
| Subject | Chagas disease | pt_BR |
| Subject | Public health | pt_BR |
| Subject | Treatment | pt_BR |
| Subject | Electron microscopy | pt_BR |
| xmlui.metadata.dc.subject.ods | 03 Saúde e Bem-Estar | |
