Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/23866
Title: Aichi Virus Positivity in HIV-1 Seropositive Children Hospitalized with Diarrheal Disease
Authors: Portes, Silvana Augusta Rodrigues
Volotão, Eduardo de Mello
Rose, Tatiana Lundgen
Rocha, Monica Simões
Xavier, Maria da Penha Trindade Pinheiro
Assis, Rosane Maria de
Fialho, Alexandre Madi
Rocha, Myrna Santos
Miagostovich, Marize Pereira
Leite, José Paulo Gagliardi
Costa, Felipe Anibal Carvalho
Affilliation: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ. Brasil.
Hospital Menino Jesus. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ. Brasil.
Abstract: Aichi viruses (AiV) have been detected in patients with diarrheal diseases (DD). The aim of this study was to assess AiV infection rates in hospitalized children with DD, including 123 HIV-1 seropositive and 125 HIV-1 seronegative patients, in two public pediatric hospitals in Rio de Janeiro, Brazil. AiV was investigated by nested RT-PCR. The AiV-positive samples were also tested for specie A rotavirus, norovirus, astrovirus, enteric adenovirus and bocavirus in order to assess co-infections. AiV parcial genome sequencing and phylogenetic analyses were performed. AiV were detected in 9/123 (7.32%) of the HIV-1 seropositive subjects and 1/125 (0.8%) of the HIV seronegative patients with DD (p = 0.019). The phylogenetic analysis of positive samples disclosed that: i) 13 samples were characterized as genotype A, with one of them being from the HIV-1 seronegative patient; ii) one sample from a HIV-1 seropositive patient was characterized as genotype B. AiV genotype A was grouped into 3 genetic clusters. Data suggest that AiV may be an opportunistic pathogen infecting children with AIDS and DD.
Keywords: Aichi virus
AIDS
Children
diarrheal disease
HIV-1
opportunistic agent
keywords: AIDS
HIV-1
Crianças
doença diarréica
agente oportunista
Kobuvirus
Issue Date: 2015
Publisher: Bentham Science Publishers
Citation: PORTES, Silvana Augusta Rodrigues; et.al. Aichi Virus Positivity in HIV-1 Seropositive Children Hospitalized with Diarrheal Disease. Current HIV Research, v.13, p.325-331, 2015.
ISSN: 1570-162X
Copyright: restricted access
Appears in Collections:IOC - Artigos de Periódicos

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