Invasive aspergillosis caused by Aspergillus terreus: an emerging opportunistic infection with poor outcome independent of azole therapy

The University of Texas M. D. Anderson Cancer Center. Department of Infectious Diseases, Infection Control and Employee Health. Houston, TX, USA.
The University of Texas M. D. Anderson Cancer Center. Department of Infectious Diseases, Infection Control and Employee Health. Houston, TX, USA / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil
The University of Texas M. D. Anderson Cancer Center. Department of Infectious Diseases, Infection Control and Employee Health. Houston, TX, USA.
The University of Texas M. D. Anderson Cancer Center. Department of Infectious Diseases, Infection Control and Employee Health. Houston, TX, USA.
The University of Texas Health Science Center at Houston. Division of Infectious Diseases. Houston, TX, USA.
The University of Texas Health Science Center at Houston. Division of Infectious Diseases. Houston, TX, USA.
The University of Texas M. D. Anderson Cancer Center. Department of Infectious Diseases, Infection Control and Employee Health. Houston, TX, USA.
The University of Texas M. D. Anderson Cancer Center. Department of Infectious Diseases, Infection Control and Employee Health. Houston, TX, USA.
The University of Texas M. D. Anderson Cancer Center. Department of Infectious Diseases, Infection Control and Employee Health. Houston, TX, USA.

Abstract

Invasive aspergillosis (IA) caused by Aspergillus terreus is a significant cause of morbidity and mortality in patients with haematological malignancy (HM). Very few data are available in this patient population to differentiate IA patients with A. terreus from those with non-terreus species of Aspergillus to compare outcomes. We retrospectively investigated 513 HM patients who were treated for either definite or probable IA between June 1993 and August 2012 in a cancer centre.

Keywords in Portuguese

Aspergillus terreus
Invasive aspergillosis
Infecção
Sulfisoxazol
Tratamento
malignidade hematológica

Keywords

A. terreus
haematological malignancy
IA
Azole therapy

Publisher

Oxford University Press

Citation

HACHEM, Ray; et al. Invasive aspergillosis caused by Aspergillus terreus: an emerging opportunistic infection with poor outcome independent of azole therapy. J Antimicrob Chemother, v.69, p.3148–3155, July 2014.

DOI

10.1093/jac/dku241

ISSN

0305-7453

Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/23951

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Copyright

Restricted access

Embargo date

2030-01-01

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