In this paper, we suggest a methodology aiming to present a longitudinal study able to present a panorama of the science coverage for 130 years by three important newspapers in Pará: A Província do Pará (1876-2002), Folha do Norte (1896-1974) and O Liberal (1946-current). We studied a period of two months every ten years, from 1876 to 2006, in each newspaper, aiming to obtain a long term view through the history of the newspapers and, thus, through most of the history of the press in Pará and in Amazon. We used content analysis and frame analysis. Our results show emphasis in health research, highlight for national science and a concern in putting the facts in context. Controversies and science uncertainties received little attention in the analysed newspapers.