Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/25506
Title: Lower survival rate, longevity and fecundity of Aedes aegypti (Diptera: Culicidae) females orally challenged with dengue virus serotype 2
Authors: Freitas, R. Maciel de
Koella, J. C.
Oliveira, R. Lourenço de
Affilliation: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Transmissores de Hematozoários. Rio de Janeiro, RJ. Brasil / Imperial College London. Division of Biology, Ascot, United Kingdom.
Imperial College London. Division of Biology, Ascot, United Kingdom.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Transmissores de Hematozoários. Rio de Janeiro, RJ. Brasil.
Abstract: As the pathogenic effects of a parasite on its hosts can strongly influence its epidemiology, we compared the life-histories of dengue virus serotype 2 (DENV-2)-infected and uninfected Aedes aegypti females. Unexposed mosquitoes lived longer than exposed ones, but those infected lived longer than exposed but negative (as assayed by Real-Time quantitative Reverse Transcription PCR [qRT-PCR]) mosquitoes. Infected mosquitoes from a long-established laboratory colony presented more viral RNA copies at death than those from the F1-generation of a field population from Rio de Janeiro. The mortality of infected colony-mosquitoes was independent of the number of viral RNA copies at death, whereas in the field population, longevity decreased with the number of viral RNA copies, suggesting that F1 of field mosquitoes are less tolerant to infection than the laboratory-colony. Infected females had a lower fecundity than controls. F1 of field mosquitoes were more likely to lay eggs than the colony; egg-laying success was strongly affected by mosquito age for both mosquito populations: from 49.28 in the first clutch to 20.7 in the fifth. Overall, DENV-2 reduced Aedes aegypti survival and fecundity, clearly affecting vectorial capacity and consequently transmission intensity.
Keywords: Aedes aegypti
Fitness
Dengue
Vectorial capacity
Cost of infection
keywords: Aedes aegypti
Dengue
Ginástica
Capacidade vetorial
Custo da infecção
Issue Date: 2011
Publisher: Elsevier
Citation: FREITAS, R. Maciel de; KOELLA, J. C.; OLIVEIRA, R. Lourenço de. Lower survival rate, longevity and fecundity of Aedes aegypti (Diptera: Culicidae) females orally challenged with dengue virus serotype 2. Transactions of the Royal Society of Tropical Medicine and Hygiene, v.105, p.452– 458, 2011.
DOI: 10.1016/j.trstmh.2011.05.006
ISSN: 0035-9203
Copyright: restricted access
Appears in Collections:IOC - Artigos de Periódicos

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