Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/25632
Title: Occupationally acquired american cutaneous leishmaniasis
Authors: Brito, Maria Edileuza Felinto de
Andrade, Maria Sandra
Almeida, Ericka Lima de
Medeiros, Angela Cristina Rapela
Werkhäuser, Roberto Pereira
Araújo, Ana Isabele Freitas de
Brandão-Filho, Sinval Pinto
Almeida, Alzira Maria Paiva de
Rodrigues, Eduardo Henrique Gomes
Affilliation: Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil / Universidade Federal de Pernambuco. Centro de Ciências Biológicas. Recife, PE, Brasil.
Universidade de Pernambuco. Departamentos de Enfermagem. Recife, PE, Brasil.
Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.
Universidade de Pernambuco. Departamentos de Enfermagem. Recife, PE, Brasil.
Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.
Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.
Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.
Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.
Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.
Abstract: WE REPORT TWO OCCUPATIONALLY ACQUIRED CASES OF AMERICAN CUTANEOUS LEISHMANIASIS (ACL): one accidental laboratory autoinoculation by contaminated needlestick while handling an ACL lesion sample, and one acquired during field studies on bird biology. Polymerase chain reaction (PCR) assays of patient lesions were positive for Leishmania, subgenus Viannia. One isolate was obtained by culture (from patient 2 biopsy samples) and characterized as Leishmania (Viannia) naiffi through an indirect immunofluorescence assay (IFA) with species-specific monoclonal antibodies (mAbs) and by multilocus enzyme electrophoresis (MLEE). Patients were successfully treated with N-methyl-glucamine. These two cases highlight the potential risks of laboratory and field work and the need to comply with strict biosafety procedures in daily routines. The swab collection method, coupled with PCR detection, has greatly improved ACL laboratory diagnosis.
Keywords: Polymerase chain reaction
PCR
Leishmaniasis cuteneuos
Leishmania
Occupational infections
Occupational disease
Biosecurity
keywords: Reações em cadeia da polimerase
PCR
Leishmania
Biossegurança
Infecções ocupacionais
Doença ocupacional
leishmaniose cutânea
DeCS: Reação em Cadeia da Polimerase
Estudo transversal
Exposição a Agentes Biológicos
Leishmaniose Cutânea / transmissão
Humanos
Brasil / epidemiologia
Contenção de Riscos Biológicos
Riscos Ocupacionais
Biossegurança / prevenção & controle
Pessoal de Saúde
Issue Date: 2012
Citation: FELINTO DE BRITO, M. E. et al. Occupationally Acquired American Cutaneous Leishmaniasis. Case Reports in Dermatological Medicine, v. 2012, p. 1–4, 2012.
DOI: 10.1155/2012/279517
ISSN: 2090-6463
Copyright: open access
Appears in Collections:PE - IAM - Artigos de Periódicos

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