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AutorLima, Sandro G. de
AutorAlbuquerque, Maria de Fátima Pessoa Militão de
AutorOliveira, João R. M. de
AutorAyres, Constância F. J.
AutorCunha, José E. G. da
AutorOliveira, Danyllo F. de
AutorLemos, Roberta R. de
AutorSouza, Manuela B. R. de
AutorSilva, Odwaldo B. e
Data de acesso2018-04-16T13:31:26Z
Data de disponibilização2018-04-16T13:31:26Z
Data do publicação2012
CitaçãoLIMA, Sandro G. de et al. Exaggerated blood pressure response during exercise treadmill testing: functional and hemodynamic features, and risk factors. Hypertension Research, v. 35, n. 7, p. 733–738, jul. 2012.pt_BR
ISSN1348-4214pt_BR
URIhttps://www.arca.fiocruz.br/handle/icict/25850
FomentoEste trabalho foi financiado pela FACEPE.pt_BR
Idiomaengpt_BR
Direito Autoralrestricted accesspt_BR
Palavras-chaveResposta exagerada da pressão arterialpt_BR
Palavras-chaveGenespt_BR
Palavras-chaveHipertensãopt_BR
Palavras-chaveFatores de riscopt_BR
TítuloExaggerated blood pressure response during exercise treadmill testing: functional and hemodynamic features, and risk factorspt_BR
Tipo do documentoArticle
DOI10.1038/hr.2012.14
Resumo em InglêsThe factors which contribute to an exaggerated blood pressure response (EBPR) during the exercise treadmill test (ETT) are not wholly understood. The association between the insertion/deletion polymorphisms of the angiotensin-converting enzyme (ACE) and M235T of the angiotensinogen with EBPR during ETT still remains unstudied. To identify and compare the risk factors for hypertension between normotensive subjects with EBPR and those who exhibit a normal curve of blood pressure (BP) during ETT. In a series of EBPR cases from a historical cohort of normotensive individuals, a univariate analysis was performed to estimate the association of the studied factors with BP behavior during ETT. Additionally, logistic multivariate regression was conducted to analyze the joint effects of the variables. P-values above 0.05 were considered statistically significant. From a total of 10,027 analyzed examinations, only 219 met the criteria employed to define EBPR, which resulted in a prevalence of 12.6%. For the systolic component of the BP, hyperreactive subjects displayed a mean age and body mass index (BMI) significantly higher than the others (P=0.002 and <0.001, respectively). No association was observed between the polymorphisms cited above and EBPR. An analysis of the joint effect of variables has indicated that only age (P< 0.001) and BMI (P=0.001) were specifically associated with systolic BP during exercise. Age and BMI were the only factors that independently influenced EBPR during ETT.pt_BR
AfiliaçãoFundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.pt_BR
AfiliaçãoFundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.pt_BR
AfiliaçãoFederal University of Pernambuco. Keizo Asami Laboratory. Recife, PE, Brazil.pt_BR
AfiliaçãoFundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.pt_BR
AfiliaçãoFederal University of Pernambuco. Keizo Asami Laboratory. Recife, PE, Brazil.pt_BR
AfiliaçãoFederal University of Pernambuco. Keizo Asami Laboratory. Recife, PE, Brazil.pt_BR
AfiliaçãoFederal University of Pernambuco. Keizo Asami Laboratory. Recife, PE, Brazil.pt_BR
AfiliaçãoFederal University of Pernambuco. Keizo Asami Laboratory. Recife, PE, Brazil.pt_BR
AfiliaçãoFederal University of Pernambuco. Department of Clinical Medicine. Recife, PE, Brazil.pt_BR
Palavras-chave em inglêsExaggerated blood pressure responsept_BR
Palavras-chave em inglêsGenespt_BR
Palavras-chave em inglêsHypertensionpt_BR
Palavras-chave em inglêsRisk Factorspt_BR
DeCSAdolescentept_BR
DeCSAdultopt_BR
DeCSEnvelhecidopt_BR
DeCSAngiotensinogênio / genéticapt_BR
DeCSPressão Arterial / genéticapt_BR
DeCSPressão Arterial / fisiologiapt_BR
DeCSEstudos de coortept_BR
DeCSTeste de Exercíciopt_BR
DeCSFêmeapt_BR
DeCSEstudos de associação genéticapt_BR
DeCSHemodinâmica / genéticapt_BR
DeCSHemodinâmica / fisiologiapt_BR
DeCSHumanospt_BR
DeCSHipertensão / genéticapt_BR
DeCSHipertensão / fisiopatologiapt_BR
DeCSMutação INDELpt_BR
DeCSMasculinopt_BR
DeCSMeia idadept_BR
DeCSPeptidil-Dipeptidase A / genéticapt_BR
DeCSPolimorfismo Genéticopt_BR
DeCSFatores de riscopt_BR
DeCSAdulto jovempt_BR
Data de embargo2050-01-01


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