Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/2641
Title: Haematophagous arthropod saliva and host defense system: a tale of tear and blood
Authors: Andrade, Bruno de Bezerril
Teixeira, Clarissa Romero
Barral, Aldina Maria Prado
Barral Netto, Manoel
Affilliation: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, Bahia, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, Bahia, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, Bahia, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, Bahia, Brasil
Abstract: The saliva from blood-feeding arthropod vectors is enriched with molecules that display diverse functions that mediate a successful blood meal. They function not only as weapons against host’s haemostatic, inflammatory and immune responses but also as important tools to pathogen establishment. Parasites, virus and bacteria taking advantage of vectors’ armament have adapted to facilitate their entry in the host. Today, many salivary molecules have been identified and characterized as new targets to the development of future vaccines. Here we focus on current information on vector’s saliva and the molecules responsible to modify host’s hemostasis and immune response, also regarding their role in disease transmission.
Keywords: Saliva
Bites
Hemostasia
Vector
Infection
Host
keywords: Saliva
Picadas
Hemostasia
Vetor
Infecção
DeCS: Vetores Artrópodes
Coagulação Sanguínea
Hemostasia
Interações Hospedeiro-Parasita
Agregação Plaquetária
Saliva
Issue Date: 2005
Citation: ANDRADE, B. B. et al. Haematophagous arthropod saliva and host defense system: a tale of tear and blood. Anais da Academia Brasileira de Ciências, v. 77, n. 4, p. 665-693, 2005.
ISSN: 0001-3765
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

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