Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/26525
Title: Chemical Composition of the Essential Oil from the Fresh Fruits of Xylopia laevigata and its Cytotoxic Evaluation
Authors: Costa, Emmanoel Vilaça
Silva, Thanany Brasil da
Costa, Cinara Oliveira D’Souza
Soares, Milena Botelho Pereira
Bezerra, Daniel Pereira
Affilliation: Amazonas Federal University. Department of Chemistry. Manaus, AM, Brazil
Sergipe Federal University. Department of Chemistry. São Cristóvão, SE, Brazil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Hospital São Rafael. Centro de Biotecnologia e Terapia Celular. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Abstract: The essential oil obtained by hydrodistillation from the fresh fruits of Xylopia laevigata was analyzed by gas chromatography using a flame ionization detector (GC􀀐FID) coupled to a mass spectrometer (GC􀀐MS). Monoterpenes predominated, forming 95.0% of the total essential oil. The major constituents identified were limonene (56.2%), 􀁄-pinene (28.0%), and 􀁅-pinene (5.5%). Cytotoxic activity against tumor cell lines and non-tumor cells was also investigated; however, neither the essential oil nor its major constituents evaluated presented any cytotoxic activity (IC50 > 25.0 􀁐g mL-1).
Keywords: Xylopia laevigata
Fresh fruits
Essential oil
Cytotoxicity activity
keywords: Xylopia laevigata
Frutas frescas
Óleo essencial
Atividade de citotoxicidade
Issue Date: 2016
Publisher: Natural Product Incorporation
Citation: COSTA, E. V. et al. Chemical Composition of the Essential Oil from the Fresh Fruits of Xylopia laevigata and its Cytotoxic Evaluation. Natural Product Communications, v. 11, n. 3, p. 417-418, 2016.
ISSN: 1934-578X
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

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