Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/2740
Title: A contribution to the pathobiology of Biomphalaria glabrata hemocytes
Authors: Borges, Claudia Maria da Cunha
Azevedo, Carine Machado
Andrade, Zilton de Araújo
Affilliation: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil
Abstract: This study attempts to investigate the relationship between the hemocytes in the two compartments: circulating peripheral lymph and the connective tissues. The hemocytes are compared with the vertebrate macrophages and constitute the principal line of defense against external aggression. The hemocytes were counted in circulating hemolymph and their phagocytic capability was evaluated in Schistosoma mansoni-infected Biomphalaria glabrata and the results were compared with those obtained from normal intact control snails. Although the number of circulating hemocytes revealed a mild increase in snails at the 6th week of infection, the overall findings were similar and pointed out that the cells in the two compartments are not functionally connected. However, the hemocytes found within the connective tissues of infected snails showed definite ultrastructural differences in the number and disposition of cytoplasmic prolongations and organelles in comparison with the hemocytes from non-infected snails. Histochemically, the staining for acid phosphatase activity served as a marker to hemocytes, sometimes being found in extracellular material at the foci of parasite-hemocyte interactions.
Keywords: Biomphalaria glabrata
Schistosoma mansoni
hemocytes
keywords: Biomphalaria glabrata
Schistosoma mansoni
hemócitos
DeCS: Schistosoma mansoni
Hemócitos
Issue Date: 2006
Citation: BORGES, C. M. da C.; AZEVEDO, C. M.; ANDRADE, Z. A. A contribution to the pathobiology of Biomphalaria glabrata hemocytes. Memórias do Instituto Oswaldo Cruz, v. 101, supl. 1, p. 193-198, 2006.
ISSN: 0074-0276
Copyright: open access
Appears in Collections:BA - IGM - Artigos de Periódicos

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