Author | Marques, Bianca Cristina Leires | |
Author | Morgado, Mariza Gonçalves | |
Author | Guimarães, Monick Lindenmeyer | |
Access date | 2018-07-10T15:13:11Z | |
Available date | 2018-07-10T15:13:11Z | |
Document date | 2018 | |
Citation | MARQUES, Bianca Cristina Leires; MORGADO, Mariza Gonçalves; GUIMARÂES, Monick Lindenmeyer. Potential overestimation of HIV-1 sub-subtype F1 circulation in Rio de Janeiro, Brazil. Mem Inst Oswaldo Cruz, v.113, n.8, e170483, 6p, 2018. | pt_BR |
ISSN | 0074-0276 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/27401 | |
Language | eng | pt_BR |
Publisher | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | HIV-1 | pt_BR |
Subject in Portuguese | Epidemiologia Molecular | pt_BR |
Subject in Portuguese | Técnicas de Genotipagem | pt_BR |
Subject in Portuguese | sub-subtipo F1 | pt_BR |
Subject in Portuguese | genoma completo | pt_BR |
Subject in Portuguese | Rio de Janeiro | pt_BR |
Title | Potential overestimation of HIV-1 sub-subtype F1 circulation in Rio de Janeiro, Brazil | pt_BR |
Type | Article | pt_BR |
DOI | 10.1590/0074-02760170483 | |
Abstract | In Brazil, detection of the HIV-1 sub-subtype F1 has decreased with a simultaneous increase in detection of the recombinant FB and FC forms. In previous HIV-1 env molecular epidemiology studies in Rio de Janeiro, 11.4% of the detected sequences were of the F1 sub-subtype. With the goal of re-estimating the prevalence of the HIV-1 F1 sub-subtype, we performed extended analyses of these samples by examining five genomic regions, resulting in 3.3% being confirmed as F1. Moreover, genomic analysis of 11 of the 21 samples identified as F1 confirmed that nine were F1 and two were BF1. Considering the number of samples assayed, the prevalence of F1 was quite low, which supports the use of different genomic regions for the assessment of HIV-1 classification in countries where several subtypes and recombinant forms co-circulate. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ. Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ. Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ. Brasil. | pt_BR |
Subject | HIV-1 | pt_BR |
Subject | sub-subtype F1 | pt_BR |
Subject | full-length genome | pt_BR |
Subject | molecular epidemiology | pt_BR |
Subject | genotyping | pt_BR |
Subject | Brazil | pt_BR |
e-ISSN | 1678-8060 | |