Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/27661
Title: Effects of Euphorbia milii Latex on Schistosoma mansoni Eggs, Miracidia and Cercariae
Authors: Carvalho, Rosangela Ribeiro de
Maldonado Junior, Arnaldo
Oliveira Filho, Eduardo Cyrino de
Ribeiro, Ana Claudia
Paumgartten, Francisco José Roma
Rey, Luiz
Affilliation: Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
Empresa Brasileira de Pesquisa Agropecuária. Brasília, DF, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Departamento de Ciências Biológicas. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
Abstract: The latex of "Crown-of-Thorns" (Euphorbia milii var hislopii) is a potent plant molluscicide and a promising alternative to niclosamide (NCL), today`s mostly used molluscicidal compound. In addition to being an effective molluscicide, NCL also kills miracidia and cercariae, the two free living stages of Schistosoma trematodes. It is active against other helminths as well. Owing to its prominent cestocide activity NCL has been used in human and veterinary medicine as a drug of choice to treat several tapeworm infections. However, the effects of E. milii on helminths have not been studied so far. In this study we investigated the effects of E. milii latex on S. mansoni eggs, miracidia and cercariae. Data on the toxicity of NCL to these developmental stages of S. mansoni were also obtained for comparative purposes.
Keywords: Niclosamide
Plant Molluscicides
Euphorbiaceae
Schistosomiasis
Euphorbia Splendens
DeCS: Niclosamide
Euphorbiaceae
Schistosomiasis
Euphorbia
Issue Date: 1998
Publisher: Casa de Oswaldo Cruz/Fiocruz
Citation: CARVALHO, R. R. et al. Effects of Euphorbia milii latex on Schistosoma mansoni eggs, miracidia and cercariae. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 93, supl. 1, p. 235-237, 1998.
DOI: 10.1590/S0074-02761998000700042
ISSN: 0074-0276
Copyright: open access
Appears in Collections:IOC - Artigos de Periódicos
ENSP - Artigos de Periódicos

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