Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/27751
Title: External Quality Assessment for Zika Virus Molecular Diagnostic Testing, Brazil
Authors: Fischer, Carlo
Pedroso, Celia
Mendrone, Alfredo
Bispo de Filippis, Ana Maria
Vallinoto, Antonio Carlos Rosário
Ribeiro, Bergmann Morais
Durigon, Edison Luiz
Marques, Ernesto T. A.
Campos, Gubio S.
Viana, Isabelle F. T.
Levi, José Eduardo
Scarpelli, Luciano Cesar
Nogueira, Mauricio Lacerda
Bastos, Michele de Souza
Souza, Nathalia C. Santiago
Khouri, Ricardo
Lira, Sanny
Komninakis, Shirley Vasconcelos
Baronti, Cécile
Charrel, Rémi N.
Kümmerer, Beate M.
Drosten, Christian
Brites, Carlos
Lamballerie, Xavier de
Niedrig, Matthias
Netto, Eduardo Martins
Drexler, Jan Felix
Affilliation: German Centre for Infection Research. Associated partner Charité–Universitätsmedizin. Berlin, Germany.
LAPI. Hospital Universitário Professor Edgard Santos. Salvador, BA, Brazil.
Fundação Pro-Sangue/Hemocentro de São Paulo. São Paulo, SP, Brazil.
Oswaldo Cruz Foundation. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brazil.
Federal University of Para. Belém, PA, Brazil.
University of Brasília. Brasília, DF, Brazil.
University of São Paulo. São Paulo, SP, Brazil.
Oswaldo Cruz Foundation. Aggeu Magalhães Institute. Pernambuco, PE, Brazil.
Federal University of Bahia. Salvador, BA, Brasil.
Oswaldo Cruz Foundation. Aggeu Magalhães Institute. Pernambuco, PE, Brazil.
Fundação Pro-Sangue/Hemocentro de São Paulo, São Paulo, SP, Brazil / University of São Paulo. São Paulo, SP, Brazil / Diagnósticos da América—DASA. São Paulo, SP, Brazil / Hospital Israelita Albert Einstein. São Paulo, SP, Brazil.
Diagnósticos da América—DASA. São Paulo, SP, Brazil.
Faculdade de Medicina de São José do Rio Preto. São José do Rio Preto, SP, Brazil.
Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, Brazil.
University of São Paulo. São Paulo, SP, Brazil.
Oswaldo Cruz Foundation. Gonçalo Muniz Institute. Salvador, BA, Brazil.
Hospital Israelita Albert Einstein. São Paulo, SP, Brazil.
Federal University of São Paulo. São Paulo, SP, Brazil.
Aix Marseille Université. Marseille, France / Assistance Publique-Hopitaux Marseille. Marseille, France.
Aix Marseille Université. Marseille, France / Assistance Publique-Hopitaux Marseille. Marseille, France.
University of Bonn Medical Centre. Bonn, Germany.
German Centre for Infection Research. Associated partner Charité–Universitätsmedizin. Berlin, Germany.
LAPI. Hospital Universitário Professor Edgard Santos. Salvador, BA, Brazil.
Assistance Publique-Hopitaux Marseille. Marseille, France / Aix Marseille Université. Marseille, France.
Robert Koch Institute. Berlin, Germany.
LAPI. Hospital Universitário Professor Edgard Santos. Salvador, BA, Brazil.
German Centre for Infection Research. Associated partner Charité–Universitätsmedizin. Berlin, Germany.
Abstract: We conducted an external quality assessment of Zika virus molecular diagnostic tests in Brazil using a new Zika virus standard. Of 15 laboratories, 73% showed limited sensitivity and specificity. Viral load estimates varied significantly. Continuous quality assurance is needed to adequately estimate risk for Zika virus-associated disease and determine patient care.
Keywords: Zika virus
Viruses
Diagnostics
Surveillance
Real-time RT-PCR
Vector-borne infections
Americas
Brazil
keywords: Vírus Zika
Vírus
Diagnósticos
Vigilância
RT-PCR em tempo real
Infecções transmitidas por vetores
Américas
Brasil
DeCS: Brasil / epidemiologia
Sensibilidade e especificidade
Zika virus / imunologia
Zika virus / crescimento & desenvolvimento
Zika virus / infecção
Zika virus / diagnóstico
Humanos
PCR em tempo real
Issue Date: 2018
Citation: FISCHER, C. et al. External Quality Assessment for Zika Virus Molecular Diagnostic Testing, Brazil. Emerging Infectious Diseases, v. 24, n. 5, p. 1-5, May 2018.
DOI: 10.3201/eid2405.171747
ISSN: 1080-6059
Copyright: open access
Appears in Collections:IOC - Artigos de Periódicos
BA - IGM - Artigos de Periódicos
PE - IAM - Artigos de Periódicos

Files in This Item:
File Description SizeFormat 
IAM - External quality assessment for Zika virus molecular diagnostic testing%2c Brazil.pdf869.04 kBAdobe PDFView/Open


FacebookTwitterDeliciousLinkedInGoogle BookmarksBibTex Format mendeley Endnote DiggMySpace

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.