Please use this identifier to cite or link to this item:
https://www.arca.fiocruz.br/handle/icict/2799
ON THE ORIGIN OF THE BIOMPHALARIA GLABRATA HEMOCYTES
Biomphalaria
Contagem de Células Sanguíneas
Movimento Celular
Hemócitos
Interações Hospedeiro-Parasita
Microscopia Eletrônica
Fagocitose
Schistosoma mansoni
Affilliation
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil
Abstract
A histologic, morphometric and ultrastructural study performed on Biomphalaria glabrata submitted to infection
with Schistosoma mansoni miracidia failed to provide significant evidences that the so-called amebocyte-producing
organ (APO) is really the central organ for hemocyte production. In infected snails no general reactive changes
appeared in the APO, the mitoses were seen only occasionally, and the possibility of cellular hyperplasia was ruled
out by morphometric measurements. Under the electron microscope the APO cells presented an essentially epithelial
structure, without features indicative of transition toward hemocytes. On the other hand, the present findings
pointed to a multicentric origin for the mollusck hemocytes, as earlier studies had indicated. Dense foci of hemocyte
collections appeared sometimes around disintegrating sporocysts and cercariae in several organs and tissues of the
infected snails, including a curious accumulation of such cells inside the ventricular cavity of the heart. In the heart
and other sites, features suggestive of transformation of vascular space endothelial lining cells into hemocytes were
apparent. To some extent, the postulated multicentric origin for B. glabrata hemocytes recapitulates earlier embryologic
findings in vertebrates, when mesenchymal vascular spaces generate the circulating and phagocytic blood
cells.
DeCS
AnimaisBiomphalaria
Contagem de Células Sanguíneas
Movimento Celular
Hemócitos
Interações Hospedeiro-Parasita
Microscopia Eletrônica
Fagocitose
Schistosoma mansoni
Share