| Author | Fonseca, Yannick de Oliveira | |
| Author | Lima, Camila Bião | |
| Author | Santos, Elisângela Trindade | |
| Author | Andrade, Zilton de Araújo | |
| Access date | 2011-08-30T13:45:19Z | |
| Available date | 2011-08-30T13:45:19Z | |
| Document date | 2011 | |
| Citation | FONSECA, Y. de O. et al. On the presence of hepatic stellate cells in portal spaces. Memórias do Instituto Oswaldo Cruz, v. 100, n. 3, p. 289-291, 2005. | pt_BR |
| ISSN | 0074-0276 | |
| URI | https://www.arca.fiocruz.br/handle/icict/2818 | |
| Language | eng | pt_BR |
| Rights | open access | |
| Subject in Portuguese | Espaço Extracelular | pt_BR |
| Subject in Portuguese | Hepatócitos | pt_BR |
| Subject in Portuguese | Cirrose Hepática | pt_BR |
| Subject in Portuguese | Sistema Porta | pt_BR |
| Subject in Portuguese | Histocitoquímica | pt_BR |
| Subject in Portuguese | Animais | pt_BR |
| Subject in Portuguese | Camundongos | pt_BR |
| Subject in Portuguese | Ratos Wistar | pt_BR |
| Title | On the presence of hepatic stellate cells in portal spaces | pt_BR |
| Type | Article | pt_BR |
| Abstract | Previous studies in mice with hypervitaminosis A have demonstrated that fat-storing cells (hepatic stellate cells-
HSCs) participate in schistosomal granuloma fibrogenesis. The origin of such cells in portal areas, away from the
Disse spaces, was herein investigated. HSCs were identified in frozen sections of the liver by means of Sudan III
staining. They appeared as red-stained cells disposed along the sinusoids of normal mice, but were never found
within portal spaces. However, in the chronically inflamed portal spaces of Capillaria hepatica-infected mice, Sudan
III-positive cells were frequently present among leukocytes and fibroblast-like cells. Thus, there are no resident
HSCs in portal spaces, but their presence there in chronic inflammatory processes indicates that they are able to
migrate from peri-sinusoidal areas in order to reach the portal areas | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
| Subject | Hepatic stelate cells | pt_BR |
| Subject | Portal fibrosis | pt_BR |
| Subject | Portal myofibroblasts | pt_BR |
| DeCS | Espaço Extracelular | pt_BR |
| DeCS | Hepatócitos | pt_BR |
| DeCS | Cirrose Hepática | pt_BR |
| DeCS | Sistema Porta | pt_BR |
