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SYSTEMIC INFLAMMATION IN SEVERE OBESE PATIENTS UNDERGOING SURGERY FOR OBESITY AND WEIGHT-RELATED DISEASES
Freitas, Wilson R et al. | Date Issued: 2018
Author
Freitas, Wilson R
Oliveira, Luis Vicente Franco
Perez, Eduardo A
Ilias, Elias J
Lottenberg, Carina P
Silva, Anderson S
Urbano, Jessica J
Oliveira, Manoel C
Vieira, Rodolfo P
Ribeiro-Alves, Marcelo
Alves, Vera L S
Kassab, Paulo
Thuler, Fabio R
Malheiros, Carlos A
Affilliation
Master’s Degree and PhD Post Graduation Program in Research in Surgery, Santa Casa of Sao Paulo Medical School, Sao Paulo, SP, Brazil
School of Medicine, University Center of Anapolis (UniEvangélica), Anapolis, Brazil
Master’s Degree and PhD Post Graduation Program in Research in Surgery, Santa Casa of Sao Paulo Medical School, Sao Paulo, SP, Brazil
Master’s Degree and PhD Post Graduation Program in Research in Surgery, Santa Casa of Sao Paulo Medical School, Sao Paulo, SP, Brazil
School of Health Sciences, Santa Casa de Sao Paulo, Sao Paulo, SP, Brazil
Sleep Laboratory, Master’s Degree and PhD Programs in Rehabilitation Sciences, Nove de Julho University (UNINOVE), Sao Paulo, SP, Brazil
Sleep Laboratory, Master’s Degree and PhD Programs in Rehabilitation Sciences, Nove de Julho University (UNINOVE), Sao Paulo, SP, Brazil
Immunology and Pulmonary Exercise Laboratory, Master’s Degree and PhD Program in Rehabilitation Sciences, Nove de Julho University (UNINOVE), Sao Paulo, SP, Brazil
Universidade Brasil, Brazilian Institute of Teaching and Research in Pulmonary and Exercise Immunology (IBEPIPE), Sao Jose dos Campos, SP, Brazil
Fundação Oswaldo Cruz.Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.
Master’s Degree and PhD Post Graduation Program in Research in Surgery, Santa Casa of Sao Paulo Medical School, Sao Paulo, SP, Brazil
Master’s Degree and PhD Post Graduation Program in Research in Surgery, Santa Casa of Sao Paulo Medical School, Sao Paulo, SP, Brazil
Master’s Degree and PhD Post Graduation Program in Research in Surgery, Santa Casa of Sao Paulo Medical School, Sao Paulo, SP, Brazil
Abstract
Obesity is a worldwide disease related to genetic, environmental, and behavioral factors, and it is associated with high rates of morbidity and mortality. Recently, obesity has been characterized by a low-grade inflammatory state known as inflammome indicated by chronic increases in circulating concentrations of inflammatory markers. The purpose of this study was to evaluate the effect of weight loss induced by surgery for obesity and weight-related diseases on pro-inflammatory cytokine (TNF-α) and anti-inflammatory adipokine (adiponectin) levels, and on an adipose-derived hormone (leptin) in severely obese subjects.
Keywords
Severe obesity
Bariatric surgical procedure
Surgery for obesity and weight-related diseases
Inflammation
Adipokines
Weight loss
Comorbidity
 
Citation
FREITAS JUNIOR, Wilson R. et al. Systemic Inflammation in Severe Obese Patients Undergoing Surgery for Obesity and Weight-Related Diseases. Obesity Surgery, v. 28, n. 7, p. 1931-1942, 2018.
DOI
10.1007/s11695-017-3104-9
ISSN
0960-8923