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2019-11-11
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CONGENITAL CMV AND HIV PERINATAL TRANSMISSION
Adachi, Kristina et al. | Date Issued: 2018
Author
Adachi, Kristina
Xu, Jiahong
Ank, Bonnie
Watts, D Heather
Camarca, Margaret
Mofenson, Lynne M.
Pilotto, Jose Henrique
Joao, Esau
Gray, Glenda
Theron, Gerhard
Santos, Breno
Fonseca, Rosana
Kreitchmann, Regis
Pinto, Jorge
Mussi-Pinhata, Marisa M.
Machado, Daisy Maria
Ceriotto, Mariana
Morgado, Mariza G.
Bryson, Yvonne J.
Veloso, Valdiléa G.
Grinsztejn, Beatriz
Mirochnick, Mark
Moye, Jack
Nielsen-Saines, Karin
NICHD HPTN 040 Study Team
Affilliation
David Geffen UCLA School of Medicine. Los Angeles, U.S.A.
Westat. Rockville, U.S.A.
David Geffen UCLA School of Medicine. Los Angeles, U.S.A.
Office of the Global AIDS Coordinator. Department of State. Washington D.C., U.S.A.
Westat. Rockville, U.S.A.
Eunice Kennedy Shriver National Institute of Child Health and Human Development. National Institutes of Health. Bethesda, U.S.A.
Hospital Geral de Nova Iguaçu. Nova Iguaçu, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
Hospital Federal dos Servidores do Estado. Rio de Janeiro, RJ, Brasil.
SAMRC and Perinatal HIV Research Unit. University of Witwatersrand. Cape Town, South Africa.
Stellenbosch University/Tygerberg Hospital. Cape Town, South Africa.
Hospital Conceição. Porto Alegre, RS, Brasil.
Hospital Femina. Porto Alegre, RS, Brasil.
Irmandade da Santa Casa de Misericórdia de Porto Alegre. Rio Grande do Sul, Brasil.
Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brasil.
Ribeirão Preto Medical School. University of São Paulo. São Paulo, SP, Brasil.
Universidade Federal de São Paulo. Escola Paulista de Medicina. São Paulo, SP, Brasil.
Foundation for Maternal and Infant Health. Buenos Aires, Argentina.
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.
David Geffen UCLA School of Medicine. Los Angeles, U.S.A.
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.
Boston University School of Medicine. Boston, U.S.A.
Eunice Kennedy Shriver National Institute of Child Health and Human Development. National Institutes of Health. Bethesda, U.S.A.
David Geffen UCLA School of Medicine. Los Angeles, U.S.A.
Abstract
Congenital cytomegalovirus (CMV) infection (cCMV) is an important cause of hearing loss and cognitive impairment. Prior studies suggest that HIV-exposed children are at higher risk of acquiring cCMV. We assessed the presence, magnitude, and risk factors associated with cCMV among infants born to HIV-infected women, who were not receiving antiretrovirals during pregnancy.
Citation
ADACHI, Kristina. et al. Congenital CMV and HIV Perinatal Transmission. The Pediatric Infectious Disease Journal, v. 37, n. 10, p. 1016-1021, 2018.
DOI
10.1097/INF.0000000000001975
ISSN
0891-3668
Notes
In addition to the authors, members of the NICHD/HPTN 040/PACTG 1043 protocol team include the following: Argentina, Buenos Aires- Foundation for Maternal and Infant Health (FUNDASAMIN): Edgardo Szyld, Silvia Marzo. Brazil, Belo Horizonte- Federal University of Minas Gerais: Flavia Faleiro Ferreira, Fabiana Kakehasi. Porto Alegre-Hospital Nossa Senhora da Conceicao: Rita Lira. Porto Alegre-Hospital Femina: Carla Franceschini de Fraga, Rita Lira. Porto Alegre-Irmandade da Santa Casa de Misericordia de Porto Alegre: Debora Fernandes Coelho, Alberto Sanseverino, Luis Carlos Ribeiro. Rio de Janeiro-Hospital dos Servidores do Estado: M. Leticia Santos Cruz, Ezequias Martins, Jacqueline Anita de Menezes, Luisa Andrea Torres Salgado. Rio de Janeiro- Hospital Geral de Nova Iguaçu: Ana Valeria Cordovil, Andréa Gouveia, Priscila Mazzucanti, Jorge Eurico Ribeiro. Ribeirao Preto -Universidade de Sao Paulo: Geraldo Duarte, Adriana Aparecida Tiraboschi Barbaro, Carolina Sales Vieira. Sao Paulo-Universidade Federal de Sao Paulo: Regina Succi. South Africa, Capetown-Stellenbosch University and Tygerberg Hospital: Mark Cotton, Jeanne Louw, Elke Maritz. Johannesburg-Perinatal HIV Research Unit, University of Witwatersrand and Chris Hani Baragwanath Hospital: Sarita Lalsab, Shini Legoete, James Alasdair McIntyre, Mandisa Nyati. United States, Baltimore-Johns Hopkins University: Allison Agwu, Jean Anderson, Joan Bess, Jonathan Ellen, Todd Noletto, Nancy Hutton. Gainesville-Shands Hospital: Carol Delany, Robert M. Lawrence. Jacksonville-University of Florida: Chas Griggs, Mobeen Rathore, Kathleen Thoma, Michelle Tucker. Long Beach- Miller Childrens Hospital: Audra Deveikis, Susan Marks. Newark-University Medical and Dental School of NJ: Linda Bettica, James M. Oleske. San Juan City-San Juan City Hospital: Midnela Acevedo Flores, Elvia Pérez. Oswaldo Cruz Foundation, Rio de Janeiro (FIOCRUZ): Ronaldo I. Moreira, Marilia Santini de Oliveira, Monica Derrico, Valéria Ribeiro, Thiago Torres e FIOTEC (Fundação para o Desenvolvimento Científico e Tecnológico). University of California-Davis: Ruth Dickover. Westat, Inc.: James Bethel, Emmanuel Aluko, Yolanda Bertucci, Jennifer Bryant, Patty Chen, Barbara Driver, Ruby Duston, Adriana Ferreira, Priya Guyadeen, Sarah Howell, Marsha Johnson, Linda Kaufman, Naomi Leshabane, Lilya Meyerson, Rita Patel, Lubima Petrova, Georgine Price, Susan Raitt, Scott Watson, Yiling Xu, Eunice Yu. Other protocol team members included Jennifer Read from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Elizabeth Smith and Sheryl Zwerski from the National Institute of Allergy and Infectious Diseases (NIAID).