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VIRAL SUPPRESSION AND HIV TRANSMISSION IN SERODISCORDANT MALE COUPLES: AN INTERNATIONAL, PROSPECTIVE, OBSERVATIONAL, COHORT STUDY
Bavinton, Benjamin R et al. | Date Issued: 2018
Author
Bavinton, Benjamin R
Pinto, Angie N
Phanuphak, Nittaya
Grinsztejn, Beatriz
Prestage, Garrett P
Zablotska-Manos, Iryna B
Jin, Fengyi
Fairley, Christopher K
Moore, Richard
Roth, Norman
Bloch, Mark
Pell, Catherine
McNulty, Anna M
Baker, David
Hoy, Jennifer
Tee, Ban Kiem
Templeton, David J
Cooper, David A
Emery, Sean
Kelleher, Anthony
Grulich, Andrew E
Opposites Attract Study Group*
Affilliation
The Kirby Institute, Sydney, NSW, Australia.
The Kirby Institute, Sydney, NSW, Australia.
PREVENTION, Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil
The Kirby Institute, Sydney, NSW, Australia.
Sydney Medical School-Westmead, University of Sydney, Sydney, NSW, Australia.
The Kirby Institute, Sydney, NSW, Australia.
Monash University, Melbourne, VIC, Australia; Melbourne Sexual Health Centre, Melbourne, VIC, Australia.
Northside Clinic, Melbourne, VIC, Australia; The Alfred Hospital, Melbourne, VIC, Australia.
Prahran Market Clinic, Melbourne, VIC, Australia.
Holdsworth House Medical Practice, Sydney, NSW, Australia.
Taylor Square Private Clinic, Sydney, NSW, Australia.
University of New South Wales, Sydney, NSW, Australia; Sydney Sexual Health Centre, Sydney, NSW, Australia.
East Sydney Doctors, Sydney, NSW, Australia.
Monash University, Melbourne, VIC, Australia; The Alfred Hospital, Melbourne, VIC, Australia.
Centre Clinic, Melbourne, VIC, Australia.
The Kirby Institute, Sydney, NSW, Australia; RPA Sexual Health, Sydney, NSW, Australia.
The Kirby Institute, Sydney, NSW, Australia; Immunology B Ambulatory Clinic, St Vincent's Hospital, Sydney, NSW, Australia.
The Kirby Institute, Sydney, NSW, Australia; Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia.
The Kirby Institute, Sydney, NSW, Australia.
The Kirby Institute, Sydney, NSW, Australia.
Abstract
Evidence on viral load and HIV transmission risk in HIV-serodiscordant male homosexual couples is limited to one published study. We calculated transmission rates in couples reporting condomless anal intercourse (CLAI), when HIV-positive partners were virally suppressed, and daily pre-exposure prophylaxis (PrEP) was not used by HIV-negative partners.
Citation
BAVINTON, B. R. et al. Viral suppression and HIV transmission in serodiscordant male couples: an international, prospective, observational, cohort study. Lancet HIV, v. 5, n. 8, p. e438-e447, 2018
DOI
10.1016/S2352-3018(18)30132-2
ISSN
2352-3018
Notes
*The Opposites Attract Study Group includes the authors listed in the byline and David Wilson (Burnet Institute, Melbourne, VIC, Australia); Kersten K Koelsch and Kathy Triffitt (Kirby Institute, University of New South Wales, Sydney, NSW, Australia); Nicolas Doong (Dr Doong’s Surgery, Sydney, NSW, Australia); and David Orth (Gladstone Road Medical Centre, Brisbane, QLD, Australia).