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2028-08-30
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- INI - Artigos de Periódicos [3193]
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EVALUATION OF XPERT MTB/RIF VERSUS AFB SMEAR AND CULTURE TO IDENTIFY PULMONARY TUBERCULOSIS IN PATIENTS WITH SUSPECTED TUBERCULOSIS FROM LOW AND HIGHER PREVALENCE SETTINGS
Xpert MTB/RIF
Nontuberculous mycobacteria
Respiratory isolation
Tuberculosis diagnosis
Author
Luetkemeyer, Anne F.
Firnhaber, Cynthia
Kendall, Michelle A.
Wu, Xingye
Mazurek, Gerald H.
Benator, Debra A.
Arduino, Roberto
Fernandez, Michel
Guy, Elizabeth
Johnson, Pamela
Metchock, Beverly
Sattler, Fred
Telzak, Edward
Wang, Yun F.
Weiner, Marc
Swindells, Susan
Sanne, Ian M.
Havlir, Diane V.
Grinsztejn, Beatriz
Alland, David
AIDS Clinical Trials Group A5295
Tuberculosis Trials Consortium Study 34 Teams
Firnhaber, Cynthia
Kendall, Michelle A.
Wu, Xingye
Mazurek, Gerald H.
Benator, Debra A.
Arduino, Roberto
Fernandez, Michel
Guy, Elizabeth
Johnson, Pamela
Metchock, Beverly
Sattler, Fred
Telzak, Edward
Wang, Yun F.
Weiner, Marc
Swindells, Susan
Sanne, Ian M.
Havlir, Diane V.
Grinsztejn, Beatriz
Alland, David
AIDS Clinical Trials Group A5295
Tuberculosis Trials Consortium Study 34 Teams
Affilliation
Division of HIV, Infectious Diseases and Global Medicine, San Francisco General Hospital, University of California. USA
Clinical HIV Research Unit Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand Right to Care, Johannesburg, South Africa.
Center for Biostatistics in AIDS Research, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Center for Biostatistics in AIDS Research, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia.
Infectious Diseases Section, Veterans Affairs Medical Center and The George Washington University, Washington D.C.
Department of Internal Medicine, Division of Infectious Diseases, The University of Texas Health Science Center at Houston.
University of North Texas Health Science Center, Tarrant County Health Department, Fort Worth.
Section of Pulmonary Critical Care and Sleep Medicine, Baylor College of Medicine, Ben Taub General Hospital, Houston, Texas.
Cepheid, Sunnyvale.
Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia.
Division of Infectious Diseases, Keck School of Medicine of USC, Los Angeles, California.
St. Barnabus Hospital Health System, Albert Einstein College of Medicine, Bronx, New York.
Emory University School of Medicine, Grady Memorial Hospital, Atlanta, Georgia.
Department of Medicine, University of Texas Health Science Center, Veterans Administration Medical Center, San Antonio.
Internal Medicine/Infectious Diseases, University of Nebraska Medical Center, Lincoln.
Right to Care, Johannesburg, South Africa Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Division of HIV, Infectious Diseases and Global Medicine, San Francisco General Hospital, University of California.
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.
Division of Infectious Disease, Rutgers New Jersey Medical School, Newark.
Clinical HIV Research Unit Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand Right to Care, Johannesburg, South Africa.
Center for Biostatistics in AIDS Research, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Center for Biostatistics in AIDS Research, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia.
Infectious Diseases Section, Veterans Affairs Medical Center and The George Washington University, Washington D.C.
Department of Internal Medicine, Division of Infectious Diseases, The University of Texas Health Science Center at Houston.
University of North Texas Health Science Center, Tarrant County Health Department, Fort Worth.
Section of Pulmonary Critical Care and Sleep Medicine, Baylor College of Medicine, Ben Taub General Hospital, Houston, Texas.
Cepheid, Sunnyvale.
Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia.
Division of Infectious Diseases, Keck School of Medicine of USC, Los Angeles, California.
St. Barnabus Hospital Health System, Albert Einstein College of Medicine, Bronx, New York.
Emory University School of Medicine, Grady Memorial Hospital, Atlanta, Georgia.
Department of Medicine, University of Texas Health Science Center, Veterans Administration Medical Center, San Antonio.
Internal Medicine/Infectious Diseases, University of Nebraska Medical Center, Lincoln.
Right to Care, Johannesburg, South Africa Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Division of HIV, Infectious Diseases and Global Medicine, San Francisco General Hospital, University of California.
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.
Division of Infectious Disease, Rutgers New Jersey Medical School, Newark.
Abstract
The Xpert MTB/RIF (Xpert) assay is a rapid nucleic acid amplification test widely used in settings of high tuberculosis prevalence to detect tuberculosis as well asrpoBmutations associated with rifampin resistance. Data are needed on the diagnostic performance of Xpert in lower-prevalence settings to inform appropriate use for both tuberculosis detection and the need for respiratory isolation.
Keywords
HIV/tuberculosis coinfectionXpert MTB/RIF
Nontuberculous mycobacteria
Respiratory isolation
Tuberculosis diagnosis
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