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NEVIRAPINE OR EFAVIRENZ FOR TUBERCULOSIS AND HIV COINFECTED PATIENTS: EXPOSURE AND VIROLOGICAL FAILURE RELATIONSHIP
Bhatt, Nilesh B. et al. | Date Issued: 2015
Author
Bhatt, Nilesh B.
Baudin, Elisabeth
Meggi, Bindiya
Silva, Carlota
Barrail-Tran, Aurélie
Furlan, Valérie
Grinsztejn, Beatriz
Bonnet, Maryline
Taburet, Anne-Marie
ANRS 12146/12214-CARINEMO Study Group
Affilliation
Ministério da Saúde. Instituto Nacional de Saúde. Maputo, Moçambique./ Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.
Epicentre. Paris, France.
Ministério da Saúde. Instituto Nacional de Saúde. Maputo, Moçambique.
Epicentre. Paris, France.
Assistance Publique Hôpitaux de Paris, Bicêtre Hospital, Hôpitaux Universitaires Paris Sud, Clinical Pharmacy. Paris, France./ University Paris Sud. Faculty of Pharmacy. Paris, France.
Assistance Publique Hôpitaux de Paris, Bicêtre Hospital, Hôpitaux Universitaires Paris Sud, Clinical Pharmacy. Paris, France.
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.
Epicentre. Paris, France.
Assistance Publique Hôpitaux de Paris, Bicêtre Hospital, Hôpitaux Universitaires Paris Sud, Clinical Pharmacy. Paris, France.
Abstract
We describe nevirapine and efavirenz exposure on and off tuberculosis treatment and consequences for virological efficacy and tolerance in patients included in the ANRS 12146/12214-CARINEMO trial.
Keywords
TB/HIV coinfection
Nevirapine
Efavirenz
Drug–drug interactions
 
Citation
BHATT, N. B. et al. Nevirapine or efavirenz for tuberculosis and HIV coinfected patients: exposure and virological failure relationship. Journal of Antimicrobial Chemotherapy, v. 70, n. 1, p. 225-232, 2015.
DOI
10.1093/jac/dku348
ISSN
0305-7453