| Author | Cortez, M. R. | |
| Author | Provençano, A. | |
| Author | Silva, C. E. | |
| Author | Mello, C. B. | |
| Author | Zimmermann, L. T. | |
| Author | Schaub, G. A. | |
| Author | Garcia, E. S. | |
| Author | Azambuja, P. | |
| Author | Gonzalez, M. S. | |
| Access date | 2018-11-08T13:44:59Z | |
| Available date | 2018-11-08T13:44:59Z | |
| Document date | 2012 | |
| Citation | CORTEZ, M. R. et al. Trypanosoma cruzi: Effects of azadirachtin and ecdysone on the dynamic development in Rhodnius prolixus larvae. Experimental Parasitology. Experimental Parasitology v.131, p.363–371, May 2012 | pt_BR |
| ISSN | 0014-4894 | pt_BR |
| URI | https://www.arca.fiocruz.br/handle/icict/29947 | |
| Language | eng | pt_BR |
| Publisher | Elsevier | pt_BR |
| Rights | restricted access | |
| Subject in Portuguese | Rhodnius prolixus | pt_BR |
| Subject in Portuguese | Trypanosoma cruzi | pt_BR |
| Subject in Portuguese | Ecdisona | pt_BR |
| Subject in Portuguese | Formas de desenvolvimento | pt_BR |
| Subject in Portuguese | Azadiractina | pt_BR |
| Title | Trypanosoma cruzi: Effects of azadirachtin and ecdysone on the dynamic development in Rhodnius prolixus larvae | pt_BR |
| Type | Article | |
| Abstract | The effects of azadirachtin and ecdysone on the Trypanosoma cruzi population in the Rhodnius prolixus gut
were investigated. T. cruzi were rarely found in the gut compartments of azadirachtin-treated larvae. High
parasite numbers were observed in the stomach of the control and ecdysone groups until 10 days after
treatment and in the small intestine and rectum until 25 days after treatment. High percentages of round
forms developed in the stomachs of all groups, whereas azadirachtin blocked the development of protozoan
intermediate forms. This effect was counteracted by ecdysone therapy. In the small intestine and
rectum, epimastigotes predominated for all groups, but more of their intermediates developed in the control
and ecdysone groups. Azadirachtin supported the development of round forms and their intermediates
into trypomastigotes. In the rectum, trypomastigotes did not develop in the azadirachtin group and
developed much later after ecdysone therapy. The parallel between the effects of azadirachtin and ecdysone
on the host and parasite development is discussed on the basis of the present results because ecdysone
appears to act directly or indirectly in determining the synchronic development of T. cruzi forms
from round to epimastigotes, but not metacyclic trypomastigotes, in the invertebrate vector. | pt_BR |
| Affilliation | Ministerio de Salud y Deportes Bolívia. Programa Nacional de Chagas. Unidad de Epidemiologia. La Paz, Bolivia. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Bioquímica de Insetos. Rio de Janeiro, RJ. Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio Grande do Sul. Instituto de Ciências Básicas da Saúde. Departamento de Microbiologia. Porto Alegre, RS, Brasil. | pt_BR |
| Affilliation | Universidade Federal Fluminense. Instituto de Biologia. Departamento de Biologia Geral. Laboratório de Biologia de Insetos. Niterói, RJ, Brasil. | pt_BR |
| Affilliation | Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Paulo de Góes. Rio de Janeiro, RJ, Brasil. | pt_BR |
| Affilliation | Ruhr- Universität Bochum. Parasitology and Zoology Group. Bochum, Germany. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Bioquímica de Insetos. Rio de Janeiro, RJ. Brasil / Instituto Nacional de Entomologia Molecular. Brasil. | pt_BR |
| Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Bioquímica de Insetos. Rio de Janeiro, RJ. Brasil / Instituto Nacional de Entomologia Molecular. Brasil. | pt_BR |
| Affilliation | Universidade Federal Fluminense. Instituto de Biologia. Departamento de Biologia Geral. Laboratório de Biologia de Insetos. Niterói, RJ, Brasil / Instituto Nacional de Entomologia Molecular. Brasil. | pt_BR |
| Subject | Rhodnius prolixus | pt_BR |
| Subject | Trypanosoma cruzi | pt_BR |
| Subject | Developmental forms | pt_BR |
| Subject | Ecdysone | pt_BR |
| Subject | Azadirachtin | pt_BR |
| e-ISSN | 1090-2449 | |
| Embargo date | 2030-01-01 | |
